China Factory Direct
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| CAS number | 127852-28-2 |
| Product name | (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing drug molecules, including antidepressants and antipsychotics | Used in asymmetric synthesis, chiral resolution, and catalytic reduction reactions |
| Pesticides | Intermediates for synthesizing active pharmaceutical ingredients (APIs) of pesticides | Applied in organic synthesis, substitution reactions, and coupling reactions |
| Advanced Materials | Preparation of optically active materials or liquid crystal display (LCD) materials | Employed in chiral modification, polymer synthesis, and functionalization reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, calibrated against certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation on a chiral stationary phase followed by UV detection; ee calculated from peak area ratio of (R)- and (S)-enantiomers. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., methanol, ethyl acetate, toluene) against external calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Digestion followed by inductively coupled plasma mass spectrometry for simultaneous quantification of Pb, Cd, Hg, As, and other regulated metals. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 600-750 C after sulfuric acid treatment; residue weighed as inorganic sulfate ash. |
| Optical Rotation | [alpha]D Measurement | Specific rotation measured at 20 C using sodium D-line (589 nm) in a defined concentration and solvent (e.g., CHCl3). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed via visual capillary method or automated melting point system per USP <741>. |
| Related Substances | HPLC-UV | Forced degradation study-compliant gradient HPLC method detecting structurally related impurities (e.g., ketone precursor, diol, dehalogenated analogs). |
| Residual Palladium | ICP-OES | Microwave-assisted acid digestion followed by inductively coupled plasma optical emission spectrometry. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by light scattering analysis to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +26.0 to +29.0° (c=1, in CHCl3) |
| Melting Point | 78.0 to 82.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.