China Factory Direct
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| CAS number | 1279032-31-3 |
| Product name | (1R,3S)-3-AMinocyclopentanol hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing antiviral or antitumor agents | Prepared via asymmetric synthesis or chiral resolution; incorporated into multistep organic synthesis to construct the target molecular scaffold |
| Pharmaceuticals | Synthesis of protease inhibitor compounds | Used as an amino alcohol building block, introduced into active molecules through acylation, condensation, and related steps |
| Pharmaceutical R&D | Critical chiral building block in lead compound optimization | Applied in medicinal chemistry for structure–activity relationship (SAR) studies and development of stereoselective synthetic routes |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state (e.g., white or off-white crystalline powder) with the naked eye to determine if it meets the specification. |
| Identification | Infrared Spectroscopy (IR) | Measure the infrared absorption spectrum of the sample and compare it with the reference spectrum to confirm the presence of characteristic functional groups (e.g., N–H, O–H, C–N, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze the chemical shifts, integration areas, and coupling constants of hydrogen atoms in the ¹H NMR spectrum to verify the molecular structure and stereochemistry. | |
| Mass Spectrometry (MS) | Determine the molecular ion peak using electrospray ionization (ESI-MS) or electron ionization (EI-MS) to confirm molecular weight and fragment information. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column and an appropriate mobile phase (e.g., phosphate buffer-acetonitrile system) for separation. Calculate the content of the main component using external standard method or area normalization method. |
| Acid-Base Titration | Utilize the H⁺ released by the hydrochloride salt in aqueous solution and titrate with a standard NaOH solution to calculate the active ingredient content (applicable for high-purity samples). | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use a gradient elution program to separate and detect potential process impurities and degradation products. Calculate impurity content using area normalization method or with correction factors. |
| Enantiomeric Purity/Optical Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column (e.g., Chiralpak AD-H, OD-H) to separate the (1R,3S) isomer from other stereoisomers and evaluate the enantiomeric excess (ee value). |
| Water Content | Karl Fischer Method | Determine the water content in the sample using volumetric or coulometric Karl Fischer titration to ensure compliance with the specified limit for loss on drying or water content. |
| Residual Solvents | Gas Chromatography (GC) | Analyze possible residual organic solvents (e.g., methanol, ethanol, dichloromethane) from the synthesis process using headspace or direct injection and polar or non-polar capillary columns. |
| Residue on Ignition/Ash Content | Gravimetric Method | Ignite the sample at high temperature until constant weight, then weigh the residual inorganic material to assess the level of inorganic impurities. |
| pH Value | pH Meter Measurement | Prepare an aqueous solution of a certain concentration and measure its pH using a calibrated pH meter to determine if it meets the specification. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After wet digestion of the sample, determine the content of heavy metals such as lead, cadmium, mercury, and arsenic using AAS or Inductively Coupled Plasma Mass Spectrometry (ICP-MS). |
| Test Item | Specification |
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| Appearance | Off-white solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | +8.0 to +10.0° (c=1, H2O) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.