China Factory Direct
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| CAS number | 127913-44-4 |
| Product name | (S)-4-Chloro-3-hydroxybutyronitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of statin intermediates | Used as a chiral building block in the asymmetric synthesis of lipid-lowering drugs, such as atorvastatin and rosuvastatin |
| Chemical Synthesis | Raw material for chiral compound synthesis | Processed into various chiral alcohols and amino acid derivatives via reduction, protection, and substitution reactions |
| Pesticides | Potential pesticide intermediate | Applied as a chiral structural unit in the synthesis of optically active insecticides or herbicides |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID | Quantification by comparison of peak area against a calibrated standard using flame ionization detection. |
| Chiral Purity (Enantiomeric Excess) | Chiral GC or Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with quantification based on peak area ratio. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based reagent. |
| Residual Solvents | GC-FID or GC-MS | Headspace or direct injection GC analysis with FID or MS detection for identification and quantification of volatile solvents. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Ion Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using suppressed conductivity detection. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized NaOH solution using phenolphthalein indicator. |
| Color | Visual Comparison or Spectrophotometry (APHA) | Comparison to platinum-cobalt standard solutions or measurement of absorbance at 430 nm. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature incineration of sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution. |
| Related Substances | HPLC-UV | Separation on reversed-phase column with UV detection at 210–220 nm and quantification relative to main peak. |
| pH of Aqueous Solution | pH Meter | Potentiometric measurement using glass electrode calibrated with standard buffer solutions. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -12.5 to -11.5 deg (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Refractive Index (n20/D) | 1.445–1.455 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.