China Factory Direct
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| CAS number | 128-53-0 |
| Product name | N-Ethylmaleimide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of pharmaceutical intermediates, including certain anticancer drugs |
| Polymer Materials | Crosslinking Agent | Applied as a crosslinking agent for rubber or plastics to enhance thermal stability and mechanical properties |
| Chemical Industry | Synthesis of Other Chemicals | Serves as a raw material for synthesizing other chemicals, such as certain polymers and resins |
| Biochemistry | Labeling Reaction | Employed in labeling reactions of biomacromolecules (e.g., proteins) to improve detection sensitivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 750–800 °C to volatilize organic matter; residual inorganic ash is weighed after cooling in desiccator. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion (HNO₃/HF), based on element-specific atomic emission intensities. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on anion-exchange column with suppressed conductivity detection, calibrated against NaCl standards. |
| Related Substances (Impurities) | HPLC-UV (with gradient elution) | Detection and quantification of structurally related impurities (e.g., N-ethylfumarimide, maleic anhydride) using optimized reverse-phase chromatographic conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using controlled heating rate (1–2 °C/min) per USP <741>. |
| Specific Optical Rotation | [α]D | Measurement of rotation of plane-polarized light at 589 nm using sodium D-line, indicating chiral purity (though NEM is achiral, detects chiral contaminants or degradation). |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein) | Neutralization of acidic impurities (e.g., hydrolyzed maleic acid derivatives) with standardized alcoholic KOH/NaOH solution. |
| Residual Solvents (e.g., Ethyl Acetate, Toluene) | GC-FID | Headspace or direct injection GC with flame ionization detection, quantified against internal standard calibration curves. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 63–67°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Odor | Characteristic mild odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.