China Factory Direct
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| CAS number | 128019-59-0 |
| Product name | N-4-Boc-2-piperazinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate in the synthesis of antidepressants and antipsychotics | Produced via reaction of piperazine-2-carboxylic acid with a Boc protecting group |
| Organic Synthesis | Synthesis of various organic compounds containing piperazine moieties | Used as a key intermediate to construct complex molecular architectures |
| Pharmaceutical R&D | Structural modification of novel drug molecules | Applied for Boc group introduction to enhance synthetic efficiency and selectivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-220 nm, comparing peak area to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., de-Boc, hydrolyzed, or isomeric by-products) using gradient HPLC and UV detection. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., DMF, THF, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Palladium | ICP-MS | Specific quantification of palladium catalyst residue post-coupling reactions using ICP-MS with internal standard correction. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Measures volatile content by weight loss after drying under controlled temperature and vacuum or air flow. |
| pH (1% w/v aqueous suspension) | pH Meter | Measures hydrogen ion activity in aqueous suspension using calibrated pH electrode per EP 2.2.3. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry or dispersed state using Mie scattering theory and laser diffraction principle. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.