China Factory Direct
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| CAS number | 128577-47-9 |
| Product name | 4-BROMOMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in the preparation of anticancer, antiviral, or central nervous system drugs | Fluoro and bromo functional groups are introduced via nucleophilic substitution or coupling reactions to construct complex drug molecular frameworks |
| Agrochemicals | Used to synthesize novel fluorinated aromatic insecticides or herbicides | Serves as a key intermediate in palladium-catalyzed Suzuki or Buchwald–Hartwig coupling reactions |
| Materials Science | Acts as a precursor for fluorinated functional polymers or liquid crystal materials | Bromomethyl groups enable polymerization or grafting reactions; carboxylate esters and fluorine atoms are incorporated to tailor material properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time comparison and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Acid Value | Acid-Base Titration | Titration with standardized sodium hydroxide solution using phenolphthalein indicator to quantify free carboxylic acid groups. |
| Bromine Content | Oxygen Flask Combustion + Potentiometric Titration | Sample combusted in oxygen flask; bromide ions absorbed and titrated with silver nitrate using potentiometric endpoint detection. |
| Fluorine Content | Ion Chromatography (IC) | After alkaline fusion or combustion, fluoride ions are separated on an anion-exchange column and detected conductometrically. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Digestion followed by multi-element quantification using inductively coupled plasma mass spectrometry with isotope dilution for accuracy. |
| Chloride Impurity | Ion Chromatography (IC) | Quantification of chloride ions after sample dissolution and filtration, using suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting and white background. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C in platinum crucible; residue weight measured after cooling in desiccator to assess inorganic ash content. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.