4-Trifluoromethylphenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 128796-39-4 |
| Product name | 4-Trifluoromethylphenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeElectronic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Trifluoromethylphenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Trifluoromethylphenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Trifluoromethylphenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents (e.g., analogues of the BTK inhibitor ibrutinib) | Used in Suzuki coupling reactions |
| Agrochemicals | Preparation of novel trifluoromethyl-containing insecticides and fungicides (e.g., trifluoromethylaniline derivatives) | Applied in palladium-catalyzed cross-coupling, followed by amination or acylation |
| Materials Science | Construction of trifluoromethyl-containing conjugated polymers to enhance thermal stability and hydrophobicity of hole-transport layers in organic light-emitting diodes (OLEDs) | Employed in Suzuki or Hiyama coupling to construct π-conjugated backbones |
| Liquid Crystal Materials | Synthesis of high-performance liquid crystal monomers to improve dielectric anisotropy and response speed | Applied in palladium-catalyzed arylation, followed by purification and crystallization |
Manufacturing Quality Control of 4-Trifluoromethylphenylboronic acid
| Milestone | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, state, and presence of foreign matter under natural light or standard illumination. It should typically appear as a white to pale white crystalline powder. |
| Purity/Content | High-Performance Liquid Chromatography (HPLC) | Use an reversed-phase C18 column with a mobile phase of methanol-water or acetonitrile-water, and detect with a UV detector (e.g., 254 nm). Calculate the main component content using external standard method or area normalization to assess sample purity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to the conditions used for purity testing, separate potential impurities (such as unreacted raw materials, by-products, degradation products) through gradient elution. Calculate the content of each impurity based on peak area and ensure it meets pharmacopoeia or company internal control standards. |
| Moisture | Karl Fischer Titration | Quantitatively determine the moisture content in the sample using the reaction between iodine and sulfur dioxide in the presence of pyridine/methylimidazole. Use coulometric or volumetric methods to assess product stability. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with FID detection. Detect residual organic solvents (e.g., toluene, dichloromethane, ethanol) during synthesis or purification according to ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Method | Fill the sample into a melting point capillary tube and heat it at a specified rate in a melting point apparatus. Record the temperature range from initial melting to complete melting to determine compound purity and consistency. |
| pH Value (if prepared as a solution) | pH Meter Method | Dissolve the sample in a certain concentration of aqueous solution (e.g., 1%) and measure its pH value using a calibrated pH meter to evaluate acidity or alkalinity against requirements. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic after sample digestion. Ensure it meets safety limits (e.g., ≤20 ppm). |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) or Titration | Quantitatively determine total boron content using ICP-OES, or indirectly measure borate group content using a mannitol-enhanced acid-base titration method to verify structural characteristics. |
Technical Specifications of 4-Trifluoromethylphenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Trifluoromethylphenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Trifluoromethylphenylboronic acid
Safety Information of 4-Trifluoromethylphenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Trifluoromethylphenylboronic acid
Industrial 4-Trifluoromethylphenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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