tert-Butyl (2R)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 128811-37-0 |
| Product name | tert-Butyl (2R)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 5KG/bag25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 128811-37-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 128811-37-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 128811-37-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing antiviral drugs (e.g., HIV protease inhibitors) | Prepared via asymmetric synthesis or chiral resolution; employed in multi-step organic synthesis to construct the target molecular scaffold |
| Pharmaceuticals | Synthesis of biologically active molecules containing a pyrrolidine moiety | Used as a protecting-group-modified amino acid derivative to introduce specific stereochemistry in solid-phase or solution-phase peptide synthesis |
| Chemical Research | Chiral building block for methodology development and exploration of new drug lead compounds | Maintains stereoselectivity in catalytic hydrogenation, cyclization, or functional group transformation reactions to support complex molecule construction |
Manufacturing Quality Control of 128811-37-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase (e.g., Chiralpak AD-H), with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, EtOAc, heptane) using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in a pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) following acid digestion and isotopic dilution or external calibration. |
| Residual tert-Butyl Alcohol | GC-FID | Specific quantification of residual t-BuOH using calibrated GC-FID with polar column and temperature programming. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., hydrolysis/decarboxylation products) under stressed conditions (acid/base/oxidative/thermal). |
| Appearance & Color | Visual Inspection / APHA Color Scale | Comparison of sample solution (in specified solvent) against APHA color standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change using calibrated capillary apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic residue after controlled ashing at 600–800 °C, followed by precise weighing. |
| Optical Rotation | [α]D Measurement | Specific rotation determination at 589 nm (Na D-line) using a digital polarimeter on a standardized solution in specified solvent. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 10% w/v in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of 128811-37-0
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in CHCl3) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 128811-37-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 128811-37-0
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Industrial 128811-37-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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