China Factory Direct
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| CAS number | 1291487-29-0 |
| Product name | 4-Aminopicolinic acid hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key structural unit in the synthesis of pyridine-containing drug active molecules (e.g., kinase inhibitors). |
| Pharmaceutical Chemicals | Molecular Scaffold Modification | Enables construction of drug molecule scaffolds or side chains via functional group transformations of the amino and carboxyl groups. |
| Biochemistry | Biological Probe Synthesis | Used to label or synthesize biologically active probe molecules for target engagement studies. |
| Organic Synthesis | Construction of Nitrogen-Containing Heterocycles | Functions as an organic synthesis reagent in coupling or cyclization reactions to prepare complex organic molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and detection of structurally related impurities (e.g., starting materials, intermediates, degradants) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatographic separation and quantification of volatile organic solvents (e.g., methanol, acetone, DMF) using flame ionization or mass spectrometric detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous pyridine/methanol medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS or ICP-OES | Multi-element quantification after acid digestion, based on elemental ion signal intensity (ICP-MS) or atomic emission intensity (ICP-OES). |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion exchange chromatography with conductivity detection, or argentometric titration using silver nitrate and potentiometric endpoint detection. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | High-temperature incineration to convert non-volatile impurities to sulfates, followed by precise weighing of residual ash. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Potentiometric measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Analysis of light scattering pattern from dispersed particles to determine volumetric size distribution in accordance with ISO 13320. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid phase transition temperature range using controlled heating and visual or automated optical detection. |
| Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution using sodium D-line source, indicating chiral purity if applicable (though compound is achiral; used for identity/counterion verification). |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 210–215 °C (decomposes) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.3% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.