1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1292836-16-8 |
| Product name | 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of fluorinated aromatic heterocyclic compounds, including molecules with antitumor, anti-inflammatory, or antimicrobial activity | Constructs the target molecular scaffold via nucleophilic substitution, reduction, or cyclization reactions |
| Agrochemical Intermediates | Serves as a precursor for synthesizing fluorinated benzyl ketone-based insecticides or herbicides | Introduces active functional groups through halogen exchange, nitro group reduction, or acyl transformation |
| Organic Synthesis Reagents | Used to construct polysubstituted benzene ring structures and participates in reactions such as Suzuki coupling and Buchwald–Hartwig amination | Leverages the directing and activating effects of chlorine, fluorine, and nitro groups for selective functional group transformations |
Manufacturing Quality Control of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., acetone, methanol, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of trace metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using mass spectrometry for element-specific detection. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Nitro Group Content | Reduction Titration (with FeSO4/KMnO4) | Indirect quantification via controlled reduction of nitro group followed by redox titration with standardized KMnO4 or FeSO4 solution. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under specified temperature and vacuum conditions, indicating volatile content. |
| Residue on Ignition | Sulfated Ash Test | Quantification of inorganic residue after high-temperature combustion in presence of sulfuric acid. |
| Particle Size Distribution | Laser Diffraction | Analysis of size distribution based on angular variation of laser light scattering from dispersed particles in air or liquid medium. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral impurities or enantiomeric excess (though compound is achiral, used for batch consistency). |
Technical Specifications of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 112–116°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
Safety Information of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone
Industrial 1-(4-Chloro-2-fluoro-5-nitro-phenyl)-ethanone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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