China Factory Direct
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| CAS number | 1297537-45-1 |
| Product name | 5-Acetyl-1H-Pyrazole-3-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of bioactive molecules or potential drug candidates | Organic synthesis, catalytic reactions, purification |
| Chemical Research | Used as a research reagent for the development and study of heterocyclic compounds or ligands | Laboratory-scale synthesis, structural modification, analytical testing |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white powder), and check for clumping or visible impurities. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with gradient elution of water and organic solvent (e.g., methanol or acetonitrile), detected by UV detector (around 254 nm) to determine the main peak purity; calculate normalized purity. |
| Content Determination | HPLC External Standard Method or Titration Method | HPLC method: Quantify by comparison with a reference standard; Titration method: If carboxyl groups are titratable, total acid content can be determined using alkaline titration. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to confirm the molecular structure, verifying characteristic peak positions of the pyrazole ring, acetyl group, and carboxylic acid functional groups. |
| Mass Spectrometry (MS) | Use ESI or EI mass spectrometry to determine molecular ion peaks ([M+H]+ or [M−H]−), confirming that the molecular weight matches the target compound. | |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Analyze characteristic absorption bands of functional groups such as C=O (acetyl and carboxylic acid), N-H, C=N, etc., to support structural confirmation. | |
| Moisture Content | Karl Fischer Titration | Determine water content using coulometric or volumetric Karl Fischer method, suitable for accurate moisture analysis in compounds containing active hydrogen. |
| Residual Solvents | Gas Chromatography (GC) | Test for solvents potentially residual from manufacturing processes (e.g., methanol, ethanol, ethyl acetate) using headspace GC; comply with ICH specification limits. |
| Melting Point | Melting Point Apparatus Method | Determine the melting temperature range using capillary tube method or automated melting point instrument for preliminary identification and purity assessment. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, detect heavy metal residues such as lead, cadmium, mercury, and arsenic; compliance with pharmacopoeial or relevant quality standards. |
| Residue on Ignition | Sulfated Ash Test | Heat the sample at high temperature followed by treatment with sulfuric acid and weigh the residue to assess inorganic impurity levels. |
| Microbial Limits | Microbial Limit Test | Perform tests according to pharmacopoeial requirements for aerobic bacterial count, mold and yeast count, and control organisms (e.g., Escherichia coli); applicable to pharmaceutical-grade products. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 178-182°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.