China Factory Direct
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| CAS number | 129799-08-2 |
| Product name | METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor agents (e.g., PARP inhibitors) and neuroactive compounds | Coupling with amines under inert atmosphere, followed by BOC deprotection under acidic conditions |
| Pharmaceuticals | Key chiral intermediate for constructing piperazine-containing protein kinase inhibitors | Participation in multi-step solid-phase or solution-phase peptide coupling reactions after chiral resolution or asymmetric synthesis |
| Pharmaceutical R&D | Structural diversity building block for high-throughput screening, used to construct piperazine-carboxylate compound libraries | Suzuki, Buchwald–Hartwig, and other cross-coupling reactions with boronic acids, haloarenes, etc., under microwave irradiation or at room temperature |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against qualified impurity standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of trace metal elements (e.g., Pb, Cd, Ni) by mass spectrometric detection after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions using an anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions using an anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C and weighing. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating purity and identity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension via scattering pattern analysis of laser beam passing through dispersed sample. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -5.0° to +5.0° (c=1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.