3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 130049-82-0 |
| Product name | 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 130049-82-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 130049-82-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 130049-82-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for the antiallergic drug potassium pemirolast | Serves as a key structural unit in the salt formation and subsequent purification steps to produce the active pharmaceutical ingredient (API) potassium pemirolast |
| Pharmaceutical Industry | Chemical synthesis API building block | Used in organic synthesis reactions to construct the pyrido[2,3-d]pyrimidinone core structure |
Manufacturing Quality Control of 130049-82-0
| Test Item | Common Testing Methods | Method Summary |
|---|---|---|
| Appearance | Visual inspection, Melting point determination | Observe physical characteristics (e.g., white to off-white crystalline powder) and odor; determine melting range using a melting point apparatus to assess purity and consistency. |
| Identification | Infrared Spectroscopy (IR), High-Performance Liquid Chromatography (HPLC) | IR: Compare characteristic absorption peaks of sample with those of a reference standard; HPLC: Confirm identity by matching retention time with that of the reference standard. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic reversed-phase HPLC to detect impurity peaks before and after the main peak; calculate impurity levels using area normalization or external standard method. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ external or internal standard method; establish a calibration curve using a reference standard of known concentration, measure the peak area of the main component, and calculate its content in the sample. |
| Water Content | Karl Fischer Titration (KF) | Use volumetric or coulometric KF titrator to accurately determine water content; suitable for thermally unstable or hygroscopic compounds. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection GC with FID or MS detection to quantitatively analyze residual organic solvents (e.g., methanol, acetonitrile) from manufacturing processes. |
| Heavy Metals | ICP-MS or Atomic Absorption Spectroscopy (AAS) | After sample digestion, measure residual levels of elements such as lead, cadmium, mercury, and arsenic to ensure compliance with ICH Q3D or pharmacopoeial limits. |
| Chloride Content (Structural Verification) | Ion Chromatography (IC) or Elemental Analysis | Verify the presence and quantity of chlorine in the molecule to confirm theoretical values, aiding structural confirmation—especially important for halogen-containing drugs. |
| Crystal Form (if applicable) | X-Ray Powder Diffraction (XRPD) | If polymorphism exists, use XRPD patterns to identify the preferred crystalline form and ensure batch-to-batch consistency in physical properties. |
| Solution Clarity and Color | Visual color comparison or UV-Visible spectrophotometry | Prepare a solution at specified concentration and visually inspect for clarity and discoloration, or measure absorbance at specific wavelengths to evaluate color intensity. |
Technical Specifications of 130049-82-0
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 130049-82-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 130049-82-0
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Industrial 130049-82-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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