China Factory Direct
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| CAS number | 130290-79-8 |
| Product name | 4-(Aminomethyl)tetrahydro-2H-pyran |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for synthesizing antiviral drugs (e.g., HIV protease inhibitors) | Introduction of the tetrahydropyran moiety via amination, cyclization, and other steps following chiral resolution or asymmetric synthesis |
| Pesticide R&D | Nitrogen-containing heterocyclic structural unit in novel insecticidal and fungicidal molecules | Participation in coupling or nucleophilic substitution reactions to construct active molecule side chains |
| Materials Science | Functional polymer monomer conferring pH responsiveness or coordination capability to polymers | Condensation with diacids/acid chlorides, or incorporation as a modified component in epoxy resin curing agents |
| Test Item | Common Testing Methods | Method Overview |
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| Identity Test | Infrared Spectroscopy (IR) Nuclear Magnetic Resonance Hydrogen Spectrum (¹H NMR) |
Confirm the structural characteristics of the compound and verify whether it is 4-aminomethyl tetrahydropyran by comparing the characteristic absorption peaks in the infrared spectrum or the chemical shift in the ¹H NMR spectrum with standard spectra. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) Gas Chromatography (GC, suitable for volatile derivatives) |
Separate and quantify the sample using reverse-phase HPLC (e.g., C18 column, UV or differential refractive index detector); or determine the main component content using GC after derivatization, calculating the content via external standard or internal standard method. |
| Related Substances/Impurity Check | High-Performance Liquid Chromatography (HPLC) | Use a gradient or isocratic elution HPLC system to separate and detect potential process impurities or degradation products, usually controlled by area normalization or main component self-reference method with correction factors. |
| Moisture | Karl Fischer Titration | Determine the moisture content accurately using volumetric or coulometric Karl Fischer titration, suitable for moisture analysis in compounds containing active hydrogen or polar groups. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, use headspace or direct injection GC-FID methods to detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) from the synthesis process. |
| Optical Rotation (if applicable) | Polarimeter Method | If 4-aminomethyl tetrahydropyran is a chiral compound and optical purity needs to be controlled, measure its optical rotation and compare it with the standard value to assess stereochemical consistency. |
| pH Value (if as a solution) | pH Meter Measurement | Prepare the sample into a specified concentration aqueous solution and measure its acidity or alkalinity using a calibrated pH meter, used to evaluate the presence of free amine and stability. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -5.0° to +5.0° (c=1, in methanol) |
| Refractive Index (n20/D) | 1.465–1.475 |
| Odor | Characteristic amine-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.