FMOC-OIC-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 130309-37-4 |
| Product name | FMOC-OIC-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-OIC-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-OIC-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-OIC-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a non-natural amino acid in peptide synthesis to construct peptide-based therapeutics with defined conformation or enhanced stability | Employed as an Fmoc-protected building block in solid-phase peptide synthesis (SPPS) for amide bond formation |
| Biochemical Research | Used to synthesize biologically active peptides containing the octahydroindole scaffold for structure–activity relationship and receptor interaction studies | Incorporated via standard Fmoc-based strategies for peptide chain elongation, followed by deprotection and purification |
| Medicinal Chemistry | Used as a chiral intermediate or structural motif in the development of protease inhibitors, G protein-coupled receptor (GPCR) ligands, and related compounds | Integrated into multi-step organic syntheses to improve metabolic stability or membrane permeability |
Manufacturing Quality Control of FMOC-OIC-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content determined by relative peak area. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, DCM, EtOAc) using flame ionization detection with headspace sampling. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue by atomic emission spectroscopy following microwave-assisted acid digestion. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm stereochemical integrity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change range using calibrated capillary method. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under specified temperature/vacuum conditions to assess volatile impurities and moisture. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-deprotected species, diastereomers) using gradient reversed-phase HPLC. |
| Residual Chloride | Ion Chromatography | Quantification of chloride ions via suppressed conductivity detection after aqueous extraction and filtration. |
Technical Specifications of FMOC-OIC-OH
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -28.0 ± 2.0° (c=1, in DMF) |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-OIC-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-OIC-OH
Packaging of FMOC-OIC-OH
Industrial FMOC-OIC-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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