13033-84-6 Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13033-84-6 |
| Product name | 13033-84-6 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 13033-84-6
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 13033-84-6 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 13033-84-6
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral intermediate for the synthesis of the antiplatelet drug ticagrelor | Serves as a key chiral building block in coupling and cyclization reactions to construct the pyrimidinyl-triazole scaffold via multistep organic synthesis |
| Pharmaceutical Industry | Chiral auxiliary or resolving agent for the preparation of other chiral pharmaceuticals | Provides a chiral environment in asymmetric synthesis or kinetic resolution to support stereochemical control |
| Food & Feed Additives | Potential sweetener enhancer or flavor-modifying ingredient (research stage; not widely commercialized) | Evaluated as an L-phenylalanine derivative analog in sensory assessment and structure–activity relationship studies |
| Chemical Research | Chiral reference standard and teaching reagent for organic synthesis in laboratory settings | Used in NMR chiral solvation, CD spectroscopy calibration, and undergraduate/graduate laboratory instruction |
Manufacturing Quality Control of 13033-84-6
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Phenylalanine Methyl Ester HCl) | HPLC with UV detection | Separation on a chiral or reversed-phase column followed by UV quantification at ~210 nm using external standard calibration. |
| Enantiomeric Purity | Chiral HPLC | Resolution of D- and L-enantiomers using a chiral stationary phase; peak area ratio determines enantiomeric excess. |
| Water Content | Karl Fischer titration | Volumetric or coulometric titration based on the reaction of iodine with water in a pyridine/methanol solvent system. |
| Residual Solvents (Methanol, Ethyl Acetate) | GC-FID | Gas chromatographic separation with flame ionization detection; quantified against certified reference standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection after acid digestion and dilution; provides sub-ppq sensitivity for regulated metals. |
| Chloride Content | Potentiometric titration with AgNO3 | Titration using silver nitrate solution with a silver/silver sulfide electrode to detect endpoint via potential change. |
| pH (1% aqueous solution) | pH meter measurement | Direct measurement of hydrogen ion activity in a standardized aqueous solution at 25 C using calibrated electrodes. |
| Related Substances | HPLC with UV detection | Separation and quantification of impurities (e.g., free D-phenylalanine, methyl ester hydrolysis products) using gradient elution. |
| Loss on Drying | Gravimetric analysis (thermogravimetry) | Weight loss measured after drying under controlled temperature and vacuum conditions for fixed time. |
| Appearance (Color & Clarity) | Visual inspection against standard solutions | Comparison of sample solution clarity and color with specified reference standards (e.g., USP <631> and <632>). |
| Residue on Ignition | Sulfated ash gravimetry | Ignition of sample at 700-800 C after sulfuric acid treatment; residual inorganic mass determined by weighing. |
| Microbial Limits | Membrane filtration and colony counting | Sample filtration, membrane transfer to selective media, incubation, and enumeration of aerobic bacteria, yeasts, and molds. |
Technical Specifications of 13033-84-6
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 162-166°C |
| Optical Rotation | -39.0 to -35.0° (c=1, in 6N HCl) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 13033-84-6
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 13033-84-6
Packaging of 13033-84-6
Industrial 13033-84-6 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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