2-Chloro-4-methylpyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13036-57-2 |
| Product name | 2-Chloro-4-methylpyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-methylpyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-methylpyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-methylpyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing sulfonylurea herbicides (e.g., bensulfuron-methyl, pyrazosulfuron-ethyl) | Constructs the pyrimidine ring side chain via nucleophilic substitution with aniline derivatives |
| Pharmaceuticals | Pyrimidine scaffold precursor for synthesizing anticancer agents (e.g., gemcitabine derivatives) and kinase inhibitors | Introduces functional groups via coupling reactions (e.g., Suzuki, Heck) involving the chlorine atom |
| Dyes | Synthetic intermediate for heterocyclic azo components in reactive dyes | Couples with diazonium salts to yield azo dyes containing a pyrimidine structure |
Manufacturing Quality Control of 2-Chloro-4-methylpyrimidine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and detect using UV detector (typically around 254 nm). Quantify the main component via external standard method or normalization based on peak area. |
| Gas Chromatography (GC) | Applicable to samples with good volatility. Use capillary columns (e.g., HP-5) and FID detection with programmed temperature ramping; calculate the percentage of the main peak area. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Optimize chromatographic conditions to achieve good separation between the main peak and impurity peaks. Detect low-level impurities (such as starting materials, intermediates, degradation products) using gradient elution to enhance resolution. |
| Moisture Content | Karl Fischer Titration | Determine moisture content using either volumetric or coulometric Karl Fischer methods. Suitable for trace moisture analysis, providing accurate and reliable results. |
| Residual Solvents | Gas Chromatography (GC) | Based on ICH guidelines, use headspace injection-GC to detect organic solvents potentially remaining from production processes (e.g., methanol, ethanol, dichloromethane). |
| Melting Point | Capillary Melting Point Method | Load the sample into a capillary tube and gradually heat it in a melting point apparatus. Observe initial and final melting temperatures to assess compound purity and consistency. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Prepare samples as potassium bromide pellets or use ATR accessory for direct measurement. Obtain characteristic absorption peaks for structural confirmation and comparison with reference standards. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹³C-NMR | Dissolve the sample in deuterated solvent (e.g., CDCl₃), then analyze molecular structure using proton and carbon NMR spectra to verify the correctness of the target compound’s structure. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Prepare solution in appropriate solvent and scan in the range of 200–400 nm to determine maximum absorption wavelength (λmax), used for qualitative or quantitative auxiliary analysis. |
Technical Specifications of 2-Chloro-4-methylpyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-methylpyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-methylpyrimidine
Packaging of 2-Chloro-4-methylpyrimidine
Industrial 2-Chloro-4-methylpyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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