China Factory Direct
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| CAS number | 130406-30-3 |
| Product name | FMOC-D-PHENYLALANINOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Biopharmaceuticals | Protecting group in peptide synthesis for manufacturing specific peptide-based drugs | Used as an Fmoc-protected derivative of D-phenylalaninol in solid-phase or solution-phase peptide synthesis, introduced into the peptide chain via coupling reactions |
| Chemical Reagents | Synthetic intermediate for constructing complex molecules containing the phenylalaninol moiety | Coupled with carboxylic acids or amines via amidation or esterification reactions |
| Organic Synthesis | Chiral building block for constructing organic molecules with defined stereochemistry | Leverages its chiral center and modifiable functional groups to enable stereoselective transformations in asymmetric synthesis |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 268 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase (e.g., Chiralpak AD-H), with UV detection and comparison to D- and L-enantiomer references. |
| Residual Solvents | GC-FID | Identification and quantification of common solvents (e.g., DMF, dichloromethane, methanol) using headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection with isotopic resolution. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues post-hydrogenation using plasma excitation and element-specific emission line intensity measurement. |
| Related Substances | HPLC-UV (Gradient) | Detection and quantification of structurally related impurities (e.g., FMOC-D-phenylalanine, deprotected amine, dimer) using gradient elution and UV detection. |
| Optical Rotation | [α]D | Measurement of specific rotation at 589 nm (Na D-line) in solution (e.g., 1% w/v in THF), confirming stereochemical integrity per pharmacopeial criteria. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by controlled heating; sharp melting range confirms crystallinity and absence of significant eutectic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution based on angular scattering intensity of laser light, reporting D10/D50/D90 values. |
| pH (1% aqueous suspension) | pH Meter | Measurement of surface proton activity in aqueous suspension, indicating residual acidic/basic impurities affecting formulation stability. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss upon controlled heating (e.g., 105 °C, 2 h) under dry nitrogen, reflecting volatile content including residual solvents and moisture. |
| Microbial Limits | Membrane Filtration + TSA/TSA+CA | Quantitative enumeration of aerobic bacteria, yeasts, and molds via filtration, membrane transfer to solid media, and colony counting per ISO 11731/Ph. Eur. 5.1.4. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 75-79°C |
| Optical Rotation | +15.0 to +17.0° (c=1, in CHCl3) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.