China Factory Direct
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| CAS number | 130752-32-8 |
| Product name | FMOC-D-ARG-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Chiral protecting group reagent for incorporation of D-arginine residues in peptide synthesis | Used in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) to construct biologically active peptide segments containing D-arginine via Fmoc deprotection strategy |
| Biochemical Research | Synthesis of non-natural amino acid-labeled peptides to investigate enzyme specificity or receptor recognition mechanisms | Functionalized peptide chain preparation prior to enzyme kinetic assays and receptor binding analysis |
| Medicinal Chemistry | Synthesis of peptidomimetic drug candidates containing D-amino acids to improve metabolic stability or bioavailability | Modular synthesis step in combinatorial library construction and structure–activity relationship (SAR) studies |
| Analytical Chemistry | Reference standard or derivatization reagent for HPLC or mass spectrometry detection of D-amino acids or peptides | Precolumn derivatization prior to chiral chromatographic separation to enhance detection sensitivity and selectivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies FMOC-D-arginine by UV absorbance at 268 nm using a reversed-phase C18 column and gradient elution with aqueous buffer/organic solvent. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., FMOC-Arg-OH diastereomer, deprotected arginine, FMOC-urea) using optimized HPLC separation and UV detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically or added stoichiometrically in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Quantifies residual solvents (e.g., DMF, DCM, methanol) using gas chromatography with flame ionization detection and internal standard calibration. |
| Heavy Metals | ICP-MS | Measures trace elemental impurities (Pb, Cd, As, Hg, etc.) by plasma ionization and mass spectrometric detection with isotope dilution or external calibration. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation at 589 nm using a polarimeter to confirm stereochemical integrity of the D-arginine moiety. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 700-800 C, expressed as percentage of sample weight. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Measures hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode and pH meter. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions by separation on an anion-exchange column with suppressed conductivity detection. |
| Loss on Drying | Thermogravimetric Analysis | Determines volatile content by measuring mass loss under controlled heating (e.g., 105 C, 2 h) in a ventilated oven. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) by filtration, culture on selective media, and colony enumeration. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry or dispersed state using Mie scattering theory and angular intensity analysis of laser light. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -11.0 to -7.0 deg (c=1, DMF) |
| Melting Point | 168 to 172 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.