China Factory Direct
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| CAS number | 13081-32-8 |
| Product name | H-D-LEU-OTBU HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in peptide synthesis and chiral drug synthesis; serves as a derivative raw material of D-leucine for constructing drug molecules | Solid-phase and solution-phase peptide synthesis |
| Organic Synthesis | Serves as a chiral building block or chiral auxiliary for synthesizing complex organic molecules with defined stereochemistry | Asymmetric synthesis |
| Chemical Reagents | Used as a pharmaceutical intermediate and biochemical reagent for laboratory-scale chemical synthesis and R&D | Laboratory-scale chemical synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Leucine tert-butyl ester hydrochloride content) | HPLC with UV detection | Quantification based on peak area comparison against reference standard using reversed-phase chromatography and UV absorbance at 210 nm. |
| Enantiomeric Purity (D-isomer excess) | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Loss on Drying (LOD) | Gravimetric thermogravimetry | Mass loss measured after drying sample at 105 C for 2 hours under controlled humidity and atmospheric pressure. |
| Residual Solvents (e.g., THF, EtOAc, MeOH) | GC-FID | Volatile organic solvents quantified by gas chromatography with flame ionization detection using headspace sampling. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution calibration. |
| Chloride Content | Potentiometric titration with AgNO3 | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential inflection corresponding to AgCl precipitation. |
| pH of Aqueous Solution (5% w/v) | pH potentiometry | Measurement of hydrogen ion activity in aqueous suspension using calibrated glass electrode and reference electrode. |
| Specific Optical Rotation | [alpha]D | Measurement of plane-polarized light rotation at 589 nm using sodium D-line; reported as degrees per dm per g/mL. |
| Residual Water Content | Karl Fischer coulometric titration | Electrochemical quantification of water via iodine generation and stoichiometric reaction with sample moisture. |
| Related Substances (impurities) | HPLC with UV detection | Identification and quantification of structurally related impurities using gradient reversed-phase HPLC and UV detection at multiple wavelengths. |
| Particle Size Distribution | Laser diffraction | Analysis of scattered laser light intensity patterns to determine volumetric particle size distribution in dry dispersion mode. |
| Microbial Contamination (Total Aerobic Count) | Membrane filtration and plate count | Viable microorganisms retained on membrane filter, transferred to agar medium, and enumerated after incubation at 30-35 C for 3-5 days. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -23.0 to -15.0 deg (c=1, in 6M HCl) |
| Melting Point | 178 to 182 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.