N-Acetylneuraminic acid Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 131-48-6 |
| Product name | N-Acetylneuraminic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for N-Acetylneuraminic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Acetylneuraminic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Acetylneuraminic acid
| Industry | Application | Process |
|---|---|---|
| Food Industry | Nutritional fortificant | Added to infant formula and functional foods as a source of sialic acid to support brain development |
| Pharmaceutical Manufacturing | Active pharmaceutical ingredient and intermediate | Used as a raw material in the synthesis of antiviral drugs (e.g., oseltamivir) and ganglioside-based therapeutics |
| Biotechnology | Cell culture supplement | Added to cell culture media to mimic the in vivo environment and promote cell growth and differentiation |
| Cosmetics | Skin-care active ingredient | Formulated into premium skincare products to enhance skin barrier function and mitigate aging |
| Research | Biochemical reagent | Used in glycobiology research as a standard or enzymatic reaction substrate for structural analysis of glycoproteins and glycolipids |
Manufacturing Quality Control of N-Acetylneuraminic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Assay | High-Performance Liquid Chromatography (HPLC) | Uses reversed-phase or ion-exchange chromatography columns coupled with UV, fluorescence (FLD), or evaporative light scattering (ELSD) detectors to quantitatively analyze Neu5Ac content in samples. Offers high sensitivity and excellent reproducibility; it is the method recommended by pharmacopoeias. |
| Content Assay | High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | Combines chromatographic separation with mass spectrometric identification for precise qualitative and quantitative analysis, particularly suitable for complex matrices with strong anti-interference capability and extremely high sensitivity. |
| Purity Analysis | Thin-Layer Chromatography (TLC) | Separates compounds on a silica gel plate followed by color development (e.g., using resorcinol reagent) to qualitatively detect the presence of impurities. Simple to perform and low-cost, ideal for preliminary screening. |
| Purity/Impurity Analysis | Capillary Electrophoresis (CE) | Separates compounds based on differences in migration rates under an electric field, particularly suitable for polar compounds such as sialic acids. Offers high resolution and minimal sample consumption. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Interprets molecular structural features through 1H-NMR and 13C-NMR spectral peaks to confirm that the target compound is N-acetylneuraminic acid; considered the gold standard for structural identification. |
| Structure Confirmation | Fourier Transform Infrared Spectroscopy (FTIR) | Verifies molecular structure by comparing characteristic absorption peaks of functional groups (e.g., amide, hydroxyl, carboxyl) with reference spectra. |
| Residual Solvents/Water Content | Gas Chromatography (GC) | Suitable for detecting volatile residual solvents; when combined with headspace sampling, it can also measure water content (though Karl Fischer titration is more commonly used for water). |
| Water Content Determination | Karl Fischer Titration | A classical method for water determination based on the quantitative reaction between iodine and water; offers high precision and is widely used in active pharmaceutical ingredient quality control. |
| Microbial Limits | Microbial Culture Method (Pharmacopoeial Method) | Performs aerobic microbial, mold/yeast counts, and control organism tests according to the Chinese Pharmacopoeia or USP guidelines to ensure microbial safety of the product. |
| Heavy Metals/Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Capable of simultaneously detecting multiple trace metal elements (e.g., Pb, As, Cd, Hg) with sensitivity at the ppb level, compliant with ICH Q3D requirements. |
Technical Specifications of N-Acetylneuraminic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystal powder |
| Purity | ≥98.0% |
| SO₂ (2% Solution) | ≤0.05% |
| pH | 1.8～2.3 |
| Loss on drying | ≤2.0% |
| Transmittance | ≥98.0% |
| Ignition residue | ≤2.0% |
| Pb | ≤1 ppm |
| As | ≤1 ppm |
| Hg | ≤0.2 ppm |
| Total plate count | ≤1000 cfu/g |
| Aflatoxin B1 | ≤5.0 μg/kg |
| Yeast & Mold | ≤100 cfu/g |
| Enterobacteriaceae | ≤60 MPN/100g |
| Staphylococcus aureus | ND |
| Salmonella | ND |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of N-Acetylneuraminic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Acetylneuraminic acid
Packaging of N-Acetylneuraminic acid
Industrial N-Acetylneuraminic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply