4,5,6,7-Tetrahydro-1H-benzoiMidazole-5-carboxylic acid hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 131020-57-0 |
| Product name | 4,5,6,7-Tetrahydro-1H-benzoiMidazole-5-carboxylic acid hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 131020-57-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 131020-57-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 131020-57-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as a pharmaceutical intermediate in the synthesis of antitumor, antiviral, and central nervous system agents | Constructs the benzimidazole ring structure via organic synthesis, followed by methylation, acidification, and other steps to prepare the target compound |
| Chemical Reagents | Employed in laboratory research as a starting material for synthesizing analogous heterocyclic compounds | Undergoes nucleophilic substitution or condensation reactions in an inert solvent, followed by hydrochloride salt formation to obtain the target product |
| Biochemical Research | Applied in structural modification and functional studies of bioactive molecules | Introduces functional groups via amidation, alkylation, and related reactions; structural confirmation is performed using mass spectrometry and nuclear magnetic resonance analysis |
| Materials Science | Used as a functional monomer in polymer material modification studies | Copolymerized with multifunctional monomers to enhance thermal stability and biocompatibility of the resulting materials |
Manufacturing Quality Control of 131020-57-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration from hydrochloride salt. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a 1% w/v aqueous suspension using calibrated pH meter with glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to obtain D10, D50, and D90 values per ISO 13320. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens using validated membrane filtration and agar culture methods. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 deg C using sodium D-line (589 nm) to confirm chiral integrity. |
Technical Specifications of 131020-57-0
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 192–196 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 131020-57-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 131020-57-0
Packaging of 131020-57-0
Industrial 131020-57-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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