3'-Hydroxypropiophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13103-80-5 |
| Product name | 3'-Hydroxypropiophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3'-Hydroxypropiophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3'-Hydroxypropiophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3'-Hydroxypropiophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing anti-inflammatory agents, antiallergic drugs, and selective COX-2 inhibitors (e.g., analogues of etoricoxib) | Introducing substituents onto the phenyl ring via Friedel–Crafts acylation or palladium-catalyzed cross-coupling, followed by selective hydroxyl protection/deprotection and reductive amination |
| Organic Synthesis | Used to construct heterocyclic compounds containing ortho-hydroxyarylacetone motifs (e.g., benzofurans, coumarin derivatives) | Condensing with aldehydes under basic conditions to form chalcone precursors, followed by cyclization; or acting as a Michael acceptor in conjugate addition reactions |
| Pesticide Development | Active substructural unit in novel insecticides and plant growth regulators | Incorporated into pyrethroid or auxin analogue scaffolds via functional group transformations such as halogenation, nitration, and amination |
Manufacturing Quality Control of 3'-Hydroxypropiophenone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and quantification of structurally related impurities (e.g., 3'-methoxypropiophenone, benzalacetone) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify low-boiling solvents (e.g., acetone, methanol, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS or AAS | Quantification of toxic elements (e.g., Pb, Cd, As, Hg) after acid digestion, using inductively coupled plasma mass spectrometry or atomic absorption spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate, per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution, indicating enantiomeric purity and identity. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content after high-temperature incineration (500–600 °C) and weighing of residual non-volatile matter. |
| Appearance (Color & Clarity) | Visual Inspection | Comparison against water-white standards and observation for particulates or haze in solution (e.g., 10% w/v in ethanol) under controlled lighting. |
| pH (Aqueous Suspension) | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension, indicating acidic/basic degradation products or residual catalysts. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying | Quantification of volatile content (moisture, solvents) by mass loss upon heating under specified temperature and vacuum/air conditions. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions (from synthesis residues) via conductivity detection or silver nitrate titration with endpoint detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after ignition with sulfuric acid pretreatment, per USP <281>. |
Technical Specifications of 3'-Hydroxypropiophenone
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 52–56 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3'-Hydroxypropiophenone
| CAS/Product ID | *Required fields | |
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NMR Spectra of 3'-Hydroxypropiophenone
Packaging of 3'-Hydroxypropiophenone
Industrial 3'-Hydroxypropiophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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