N-[(tert-Butoxy)carbonyl]-L-tryptophan Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13139-14-5 |
| Product name | N-[(tert-Butoxy)carbonyl]-L-tryptophan |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-[(tert-Butoxy)carbonyl]-L-tryptophan
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-[(tert-Butoxy)carbonyl]-L-tryptophan Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-[(tert-Butoxy)carbonyl]-L-tryptophan
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | L-Tryptophan protecting reagent for peptide-based drug synthesis | In solid-phase peptide synthesis (SPPS), the indole nitrogen of tryptophan is selectively protected with a Boc group to prevent side reactions; deprotection is subsequently performed using trifluoroacetic acid (TFA) |
| Biochemical Research | Amino acid modification intermediate for protein structure and function studies | Used to prepare isotopically or fluorescently labeled tryptophan derivatives; after Boc protection, derivatization reactions—including coupling and reductive amination—are carried out |
| Diagnostics Reagent Development | Building block for tumor-targeting peptides and molecular probes | Serves as a key chiral synthon in synthesizing RGD-like peptides or neuroendocrine tumor-targeting peptides (e.g., DOTA-TATE analogues); Boc protection is introduced prior to coupling to enhance coupling selectivity |
Manufacturing Quality Control of N-[(tert-Butoxy)carbonyl]-L-tryptophan
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at 280 nm using reverse-phase C18 column and gradient elution with aqueous buffer/organic solvent. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities (e.g., Boc-deprotected, racemized, or hydrolyzed forms) using validated HPLC method with suitable resolution. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separating L- and D-enantiomers on a chiral stationary phase with UV detection. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., THF, DMF, ethyl acetate) using headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Measures trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion by detecting elemental ions via mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Quantifies inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Optical Rotation | Polarimetry | Measures specific rotation at 20 deg C using sodium D-line to confirm chiral integrity and concentration. |
| pH of Solution | Potentiometric pH Measurement | Determines acidity/basicity of a defined aqueous suspension or solution using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution based on light scattering patterns. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity against standard reference under controlled lighting and viewing conditions. |
Technical Specifications of N-[(tert-Butoxy)carbonyl]-L-tryptophan
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 235-240 °C |
| Optical Rotation | -22 to -18 ° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-[(tert-Butoxy)carbonyl]-L-tryptophan
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-[(tert-Butoxy)carbonyl]-L-tryptophan
Safety Information of N-[(tert-Butoxy)carbonyl]-L-tryptophan
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-[(tert-Butoxy)carbonyl]-L-tryptophan
Industrial N-[(tert-Butoxy)carbonyl]-L-tryptophan Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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