BOC-L-Leucine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13139-15-6 |
| Product name | BOC-L-Leucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-L-Leucine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-L-Leucine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-L-Leucine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a protected amino acid intermediate in peptide synthesis | BOC (tert-butoxycarbonyl) protection of the α-amino group of leucine in solid-phase or solution-phase peptide synthesis to prevent side reactions; the protecting group is subsequently removed via acidolysis |
| Biochemical Research | Synthesis of custom peptides or protein mimetics containing leucine residues | Employed as a building block in combinatorial chemistry or fragment coupling strategies to participate in amide bond formation reactions |
| Pharmaceutical Manufacturing | Key raw material for synthesizing therapeutic peptide drugs | Applied in controlled condensation steps during GMP-compliant production of peptide APIs (active pharmaceutical ingredients) to ensure stereochemical selectivity and purity |
| Diagnostics Reagent Development | Construction of antigenic epitope peptides for immunoassays | Leucine residues are precisely incorporated using Fmoc/BOC orthogonal protection strategies to maintain epitope conformation |
Manufacturing Quality Control of BOC-L-Leucine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Chiral Purity | Chiral HPLC | Separation and quantification of L- and D-enantiomers using a chiral stationary phase and UV detection. |
| Loss on Drying | Gravimetric method (105 C, 2 h) | Measurement of mass loss after drying under controlled temperature and time to determine volatile content including moisture. |
| Residual Solvents | Gas Chromatography (GC-FID) | Identification and quantification of organic solvents (e.g., ethyl acetate, methanol) by retention time and peak area calibration. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Impurity | Potentiometric titration with AgNO3 | Titration using silver nitrate with endpoint detection via silver ion-selective electrode. |
| Sulfate Impurity | Barium chloride turbidimetry | Formation of BaSO4 precipitate; quantification by measuring turbidity at fixed wavelength. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution. |
| pH of Solution (5% w/v) | pH meter measurement | Determination of hydrogen ion activity in aqueous suspension using calibrated glass electrode. |
| Residue on Ignition | Gravimetric method (550 C, 1 h) | Mass of non-volatile inorganic residue remaining after high-temperature ashing. |
| Related Substances | HPLC with gradient elution | Detection and quantification of structurally similar impurities (e.g., BOC-glycine, deprotected leucine) using UV detection. |
| Microbial Contamination | Membrane filtration and plate count | Enumeration of aerobic mesophilic microorganisms after filtration, incubation on nutrient agar, and colony counting. |
Technical Specifications of BOC-L-Leucine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 136-139 °C |
| Optical Rotation | -26 to -24 deg (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-L-Leucine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-L-Leucine
Packaging of BOC-L-Leucine
Industrial BOC-L-Leucine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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