BOC-L-Isoleucine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13139-16-7 |
| Product name | BOC-L-Isoleucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-L-Isoleucine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-L-Isoleucine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-L-Isoleucine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protective amino acid intermediate for synthesizing peptide-based drugs | Used to incorporate L-isoleucine residues in solid-phase or solution-phase peptide synthesis; the amino group is protected with BOC (tert-butoxycarbonyl) to prevent side reactions |
| Biochemical Research | Preparation of custom peptides containing isoleucine | Serves as a building block during peptide chain elongation, participating in automated or manual peptide synthesis via iterative deprotection-coupling cycles |
| Organic Synthesis | Chiral building block for synthesizing complex molecules | Leverages its chiral center and protecting groups to construct target compounds with defined stereochemistry in asymmetric synthesis |
Manufacturing Quality Control of BOC-L-Isoleucine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (BOC-L-Isoleucine content) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at 210 nm. |
| Enantiomeric Purity | Chiral HPLC | Separation of L- and D-isomers on a chiral stationary phase; quantification via peak area ratio to determine enantiomeric excess. |
| Loss on Drying | Gravimetric thermogravimetry | Mass loss measured after drying at 105 C for 2 hours under atmospheric pressure, indicating volatile impurities and residual solvents. |
| Residual Solvents (e.g., THF, DMF, EtOAc) | GC-FID | Separation and quantification of volatile organic solvents using gas chromatography with flame ionization detection against internal/external standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace metals after acid digestion, based on elemental mass-to-charge ratios and isotopic detection. |
| Chloride Content | Potentiometric titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential jump due to AgCl precipitation. |
| Sulfate Content | Turbidimetric assay | Formation of barium sulfate precipitate in acidic medium; quantification via measurement of turbidity at 420 nm. |
| pH of 5% Aqueous Solution | Potentiometric pH measurement | Determination of hydrogen ion activity using calibrated glass electrode in a standardized aqueous suspension. |
| Specific Optical Rotation | [alpha]D measurement | Measurement of plane-polarized light rotation at 589 nm using a digital polarimeter; reported as degrees per dm per g/mL. |
| Related Substances | HPLC with gradient elution | Separation and quantification of structurally related impurities (e.g., BOC-glycine, deprotected isoleucine) using UV detection. |
| Water Content | Karl Fischer titration | Coulometric or volumetric determination of water based on iodine consumption in a pyridine-methanol solvent system. |
| Microbial Contamination | Membrane filtration and plate count | Enumeration of aerobic mesophilic microorganisms following filtration, membrane transfer to TSA, and incubation at 30-35 C for 5 days. |
Technical Specifications of BOC-L-Isoleucine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146 °C |
| Optical Rotation | +2.5 to +3.0 ° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-L-Isoleucine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-L-Isoleucine
Packaging of BOC-L-Isoleucine
Industrial BOC-L-Isoleucine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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