China Factory Direct
|
|
| CAS number | 13139-28-1 |
| Product name | Z-VAL-NH2 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of angiotensin-converting enzyme (ACE) inhibitors (e.g., perindopril) | Peptide synthesis, condensation reaction, purification |
| Biochemistry | Used in protein structural studies and enzyme substrate mimicry | Solid-phase synthesis, liquid-phase synthesis |
| Academic Research | Chiral synthon and protecting group in organic synthesis experiments | Catalytic hydrogenation, deprotection reaction |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 210–220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/MS | Separation and identification of impurities (e.g., CBZ-L-valine, diastereomers, hydrolysis/degradation products) using gradient HPLC coupled with UV and mass spectrometric detection. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination via chiral stationary phase chromatography, resolving L- and D-valinamide diastereomers or enantiomers. |
| Residual Solvents | GC-FID | Quantitative analysis of residual solvents (e.g., methanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection against internal standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water content based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-pptr sensitivity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content by high-temperature incineration (500–600 °C) followed by precise weighing of residual residue. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity and identity via measurement of rotation angle of plane-polarized light in solution at specified concentration, temperature, and wavelength (e.g., Na D-line). |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Direct pH measurement using calibrated glass electrode in a standardized aqueous suspension/solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie theory-based light scattering to determine D10, D50, D90 values. |
| Microbial Limits | Membrane Filtration & Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods (USP <61>, <62>). |
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +23.0 to +25.0 deg (c=1, in methanol) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Conforms to reference spectrum |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.