(2S,4R)-1-(tert-butoxycarbonyl)-4-((2-(4-isopropoxyphenyl)benzofuro[3,2-d]pyrimidin-4-yl)oxy)pyrrolidine-2-carboxylicacid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1315326-78-3 |
| Product name | (2S,4R)-1-(tert-butoxycarbonyl)-4-((2-(4-isopropoxyphenyl)benzofuro[3,2-d]pyrimidin-4-yl)oxy)pyrrolidine-2-carboxylicacid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1315326-78-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1315326-78-3 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1315326-78-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing selective kinase inhibitors (e.g., JAK inhibitors) | Multi-step organic synthesis involving Suzuki coupling, benzofuran ring construction, and Boc protecting group introduction, followed by final coupling of the 4-(2-(4-isopropoxyphenyl)benzofuro[3,2-d]pyrimidin-4-yloxy) fragment with a (2S,4R)-1-(tert-butoxycarbonyl)pyrrolidine derivative |
Manufacturing Quality Control of 1315326-78-3
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at specified wavelength, comparing peak area to reference standard. |
| Chiral Purity | (S,S)/(R,R) Diastereomer Content | Chiral HPLC |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, DMF, EtOAc) using gas chromatography with flame ionization detection against calibration standards. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Determines palladium residue from catalytic steps via inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., deprotected, hydrolyzed, or oxidation products) using gradient HPLC-UV. |
| Appearance | Visual Inspection | Assesses physical form, color, and homogeneity of solid material under controlled lighting against defined reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder using light scattering principles and Mie theory. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying under controlled temperature and vacuum conditions. |
Technical Specifications of 1315326-78-3
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 212–216°C |
| Optical Rotation | +42.0 to +46.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1315326-78-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 1315326-78-3
Industrial 1315326-78-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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