FMOC-D-THR(BZL)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 131545-63-6 |
| Product name | FMOC-D-THR(BZL)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-THR(BZL)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-THR(BZL)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-THR(BZL)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Protecting reagent for D-threonine residues in solid-phase peptide synthesis (SPPS) | Used as an amino acid derivative to provide α-amino protection (Fmoc) and side-chain hydroxyl protection (O-benzyl) in Fmoc-based SPPS for synthesizing chiral peptides containing D-threonine, such as therapeutic peptides or probes |
| Biomedical Research | Structural studies and functional validation of chiral peptides and glycopeptides | Applied in laboratory-scale peptide synthesis, enabling orthogonal deprotection: Fmoc removal under basic conditions (e.g., piperidine) and O-benzyl removal via hydrogenolysis or strong acid treatment (e.g., H₂/Pd-C or TFA), while maintaining D-configuration stability |
Manufacturing Quality Control of FMOC-D-THR(BZL)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, methanol, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As, etc.) by inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-MS | Specific quantification of Pd catalyst residue using isotope-dilution ICP-MS following microwave-assisted digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual solids. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and laser diffraction optics. |
| Microbial Limits | Membrane Filtration | Assesses total aerobic microbial count and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| pH of Aqueous Suspension | Potentiometric Titration | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode and pH meter. |
Technical Specifications of FMOC-D-THR(BZL)-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -21±2.5° (c=1, in DMF) |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-THR(BZL)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-THR(BZL)-OH
Packaging of FMOC-D-THR(BZL)-OH
Industrial FMOC-D-THR(BZL)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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