China Factory Direct
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| CAS number | 13183-79-4 |
| Product name | 5-Mercapto-1-methyltetrazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Intermediate in the synthesis of cephalosporin antibiotics | Serves as a key intermediate in synthesizing β-lactam antibiotics such as cefotetan and cefamandole, participating in cyclization and substitution reactions |
| Fine Chemicals | Organic synthesis reagent | Used to construct nitrogen-containing heterocyclic compounds; participates in coupling and cyclization reactions to prepare functional molecules |
| Coordination Chemistry | Metal ligand | Coordinates with transition metals via thiol and nitrogen atoms to prepare metal complexes for catalysis or materials research |
| Test Item | Common Testing Methods | Method Overview |
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| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with gradient elution using water-methanol or acetonitrile. The main peak area is detected by UV detector (210–254 nm). Content is calculated using external or internal standard method, effectively separating impurities. |
| Impurity Profile (Related Substances) | HPLC-UV / HPLC-MS | Gradient elution HPLC combined with UV or mass spectrometry detection is used to identify and quantify known impurities (e.g., oxidation products, unreacted starting materials, dimers), in compliance with ICH Q3B guidelines. |
| Moisture Content | Karl Fischer Titration | Measures trace moisture in the sample through a quantitative reaction between water and an iodine-sulfur dioxide-pyridine-methanol system, suitable for controlling quality risks caused by hygroscopicity of the drug substance. |
| Sulfur Content (Thiol Quantification) | Iodometric Titration / Colorimetric Method (DTNB Method) | Utilizes the reaction of thiol groups (–SH) with iodine or 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB) to form a yellow product. Thiol content is quantified via titration or spectrophotometry (412 nm). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, AAS or ICP-MS is used to determine the content of heavy metal elements such as lead, cadmium, mercury, and arsenic, in compliance with pharmacopoeia limits (e.g., ICH Q3D). |
| Residual Solvents | Gas Chromatography (GC) | Residual organic solvents such as ethanol, acetone, DMF, and acetonitrile are detected using headspace or direct injection GC-FID. Compliance with ICH Q3C standards is evaluated. |
| Melting Point | Melting Point Apparatus | The melting point range of the sample is measured by capillary method or automatic melting point apparatus (literature value ~158–162°C), used for preliminary identification and purity evaluation. |
| pH Value (Aqueous Solution) | pH Meter | The sample is prepared into a solution of specified concentration (e.g., 1% w/v), and the pH is measured using a calibrated pH meter to assess the impact of acidity/alkalinity on stability. |
| Particle Size Distribution (if solid powder) | Laser Diffraction / Microscopy | Applicable for powder samples to evaluate particle size distribution and its impact on dissolution and formulation processes, ensuring batch-to-batch consistency. |
| Inorganic Impurities (e.g., Chlorides, Sulfates) | Precipitation Turbidimetry (Pharmacopoeia Method) | After dissolving the sample in water, silver nitrate or barium chloride is added to produce a precipitate. The turbidity is compared with standard solutions to control the content of inorganic anion impurities. |
| Infrared Spectroscopy (IR) Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | The infrared absorption spectrum of the sample is collected and compared with reference spectra to confirm molecular structural features (e.g., –SH, tetrazole ring vibrations), used for qualitative identification. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 168-172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.