(S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 131852-53-4 |
| Product name | (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key Chiral Intermediate | Used in the synthesis of antiviral protease inhibitors such as atazanavir |
| Pharmaceutical Industry | Chiral Building Block | Applied to construct chiral drug molecules containing a pyrrolidine scaffold |
| Pharmaceutical Industry | Drug Discovery | Serves as a structural unit in asymmetric synthesis for new drug screening |
| Chemical Industry | Asymmetric Synthesis Reagent | Used as a chiral source or ligand precursor in catalyzed asymmetric synthesis reactions |
Manufacturing Quality Control of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-230 nm based on peak area comparison with reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Measures enantiomeric purity by separating (S)- and (R)-enantiomers on a chiral stationary phase and calculating ee from peak areas. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., toluene, THF, ethyl acetate) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generated in situ via reaction with water in pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion by measuring isotopic mass-to-charge ratios with high sensitivity and multi-element capability. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection relative to calibration curve. |
| Residual Palladium | ICP-OES | Measures palladium residue post-catalytic hydrogenation by plasma excitation and emission intensity measurement at characteristic wavelength (e.g., 340.458 nm). |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., de-Boc, N-benzyl, dimer) using gradient HPLC with UV detection and threshold-based reporting. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation at 20 C using sodium D-line (589 nm) to confirm chiral integrity and batch-to-batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition using controlled heating rate; narrow range indicates high crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity of solid material against established reference standard under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of bulk powder by analyzing angular variation in laser light scattering intensity across a defined size range. |
Technical Specifications of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | -25.0 to -29.0° (c=1, in CHCl3) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
Safety Information of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE
Industrial (S)-(-)-1-BENZYL-3-(BOC-AMINO)PYRROLIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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