Methyl (E)-2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxyacrylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 131860-97-4 |
| Product name | Methyl (E)-2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxyacrylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 131860-97-4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 131860-97-4 Supplier from China
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Industrial Applications of 131860-97-4
| Industry | Application | Process |
|---|---|---|
| Pesticides | As a fungicidal intermediate for synthesizing strobilurin fungicides such as azoxystrobin | Prepared via condensation, substitution, and other organic synthesis steps to yield the target fungicidal molecule |
| Pharmaceuticals | A potential pharmaceutical intermediate for researching biologically active pyrimidine derivatives | Used as a building block in heterocyclic compound synthesis for lead compound screening or optimization |
| Fine Chemicals | A structural unit for synthesizing high-performance agrochemicals and functional materials | A key intermediate in multistep organic synthesis, participating in reactions such as Suzuki coupling and nucleophilic substitution |
Manufacturing Quality Control of 131860-97-4
| Detection Item | Common Detection Method | Method Overview |
|---|---|---|
| Identification (Identity) | Infrared Spectroscopy (IR) | Confirm compound structure by characteristic functional group absorption peaks (e.g., C=O, C=C, C–O, C–Cl, etc.). |
| ¹H Nuclear Magnetic Resonance (¹H NMR) | Analyze hydrogen atom chemical shifts, coupling constants, and integration ratios to verify molecular structure and (E)-configuration. | |
| Mass Spectrometry (MS) | Determine molecular ion peak ([M+H]⁺ or [M]⁺) and fragment ions to confirm molecular weight and partial structural information. | |
| Content Determination (Assay) | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (typically at 254 nm or based on the maximum absorption wavelength), and quantify the main component using external standard method or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Under the same chromatographic conditions, separate and quantify potential process impurities, degradation products (e.g., cis isomers, hydrolysis products, etc.), typically using self-reference method or main component self-reference method with correction factor. |
| E/Z Isomer Purity | HPLC or ¹H NMR | HPLC can separate E/Z isomers; in ¹H NMR, the coupling constant of the alkene protons (J ≈ 12–16 Hz for E configuration) can be used to determine the configuration purity. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with FID detector, and detect residual organic solvents used in synthesis (e.g., methanol, dichloromethane, ethyl acetate, etc.) according to ICH Q3C guidelines. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight, and determine the percentage loss of volatile substances (including water and solvents). |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the compound as a physical constant for identification and initial purity assessment. |
| Elemental Analysis (Optional) | Elemental Analyzer (CHNS/O) | Determine the content of C, H, N, Cl, etc., and compare it with theoretical values to verify the consistency of the compound composition. |
Technical Specifications of 131860-97-4
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128.0–132.0°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 131860-97-4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 131860-97-4
Packaging of 131860-97-4
Industrial 131860-97-4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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