China Factory Direct
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| CAS number | 131968-74-6 |
| Product name | (2R,3S)-3-phenylisoserine methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for the production of antidepressants such as venlafaxine | Chemical synthesis of the target compound from (2R,3S)-3-phenylisoserine methyl ester, involving steps including condensation and reduction |
| Chemicals | Chiral building block for organic synthesis | Used in asymmetric synthesis reactions to introduce stereospecific chiral centers, thereby enhancing product selectivity and purity |
| Research | Tool compound for studying bioactive substances | Employed under laboratory conditions as a foundational material in investigations of biological pathways or new drug development, typically through reactions with other reagents to assess diverse biological effects |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification via UV absorption at characteristic wavelength using a calibrated external standard and chiral column for enantiomeric specificity. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation of (2R,3S) and diastereomeric/isomeric impurities on a chiral stationary phase with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection against certified standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based medium. |
| Heavy Metals | ICP-OES | Multi-element detection of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Methanol | GC-FID | Direct headspace GC analysis targeting methanol content relative to internal standard. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related degradants and synthetic intermediates using gradient reverse-phase HPLC. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light source in solution at controlled temperature and concentration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via visual observation of solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined reference standards under controlled lighting. |
| pH (1% w/v aqueous solution) | pH Meter | Measurement of hydrogen ion activity in aqueous suspension using calibrated glass electrode system. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 146°C |
| Optical Rotation | +15.0° to +17.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.