Benzydamine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 132-69-4 |
| Product name | Benzydamine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Benzydamine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Benzydamine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Benzydamine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Nonsteroidal Anti-inflammatory Drugs (NSAIDs) | Used as an indole derivative to exert anti-inflammatory and analgesic effects by inhibiting prostaglandin synthesis and stabilizing lysosomal membranes. |
| Pharmaceutical Industry | Local Anesthetics | Applied to neuronal cell membranes to block nerve impulse conduction, thereby producing local anesthesia. |
| Pharmaceutical Industry | Oral and Pharyngeal Formulations | Formulated into mouthwashes, sprays, or lozenges for the treatment of oral mucositis, pharyngitis, and tonsillitis. |
| Pharmaceutical Industry | Dermatological Treatments | Formulated into creams or gels to alleviate swelling and pain associated with musculoskeletal disorders, soft tissue injuries, and inflammatory skin conditions. |
| Personal Care Industry | Oral Care Additive | Incorporated into mouthwash or toothpaste formulations to maintain oral hygiene through its antibacterial and anti-inflammatory properties. |
| Research Sector | Pharmacological Research Tool Compound | Employed in studies of inflammatory mechanisms, pain transmission pathways, and structure–activity relationships of indole derivatives. |
Manufacturing Quality Control of Benzydamine hydrochloride
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the sample with standard spectra to confirm molecular structure consistency by comparing characteristic absorption peaks. |
| UV-Visible Spectrophotometry (UV-Vis) | Determine the maximum absorption peak at a specific wavelength (e.g., around 258 nm) for preliminary identification. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with an appropriate mobile phase (e.g., methanol-buffer solution) and UV detector for quantification of the main component. |
| Non-aqueous Titration | Perform titration in a non-aqueous medium (e.g., glacial acetic acid) using perchloric acid standard solution, suitable for basic drugs. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate degradation products and synthetic intermediates via gradient or isocratic elution, detect and limit each impurity peak. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from the production process (e.g., methanol, ethanol, acetone) according to ICH guidelines. |
| Moisture | Karl Fischer Titration | Determine moisture content precisely by reacting iodine and sulfur dioxide with water in an anhydrous environment. |
| Solution Clarity | Visual Turbidimetry | Dissolve the sample in a specified solvent and compare it with a standard turbidity solution to assess presence of insoluble particles. |
| Solution Color | Visual Colorimetry or Spectrophotometry | Compare with standard color solutions or scan in the visible light region to evaluate whether the solution color meets the limit requirements. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting using a melting point apparatus to verify purity and chemical consistency. |
| Dry Loss | Thermogravimetric Analysis or Drying Method | Dry the sample at a specified temperature until constant weight is achieved and calculate the percentage of weight loss to reflect the content of volatile components. |
| Residue on Ignition | Sulfuric Acid Incineration Method | Weigh the residue after high-temperature incineration of the sample to detect inorganic impurities. |
| Heavy Metals | Thioacetamide Method (Chinese Pharmacopoeia Method) | Under weakly acidic conditions, heavy metals react with thioacetamide to form colored sulfides, which are compared with a lead standard solution for limit control. |
| Microbial Limit | Microbial Limit Test (Culture Method) | Determine total aerobic bacteria, mold, and yeast counts according to pharmacopoeia requirements, and test for controlled organisms (e.g., Escherichia coli, Salmonella). |
Technical Specifications of Benzydamine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C - 152°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Benzydamine hydrochloride
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NMR Spectra of Benzydamine hydrochloride
Packaging of Benzydamine hydrochloride
Industrial Benzydamine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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