China Factory Direct
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| CAS number | 1321-40-0 |
| Product name | 2-HYDROXYQUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antimalarial agents, antimicrobials, and kinase inhibitors | Introduced into target drug molecules via substitution, condensation, or metal-catalyzed coupling reactions to construct the quinoline scaffold |
| Agrochemicals | Used as an intermediate for fungicides and plant growth regulators | Structurally modified through halogenation, alkylation, or acylation to enhance biological activity and selectivity |
| Materials Science | Used in the preparation of organic light-emitting materials (OLEDs) and fluorescent probes | Acting as a ligand to form photoelectrically active coordination complexes with metal ions (e.g., Zn²⁺, Al³⁺) |
| Analytical Chemistry | Used as a colorimetric reagent or extractant for metal ions (e.g., Fe³⁺, Cu²⁺) | Leveraging its ability to form colored complexes with metal ions for colorimetric analysis or solvent extraction separation |
| Dye Industry | Used as a structural unit in functional dyes or fluorescent brighteners | Chromophores introduced via diazotization, coupling, or sulfonation to tune absorption and emission wavelengths |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 2-hydroxyquinoline by separation on a reversed-phase column and UV detection at ~310 nm, using external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., quinoline, 2-chloroquinoline, oxidation products) via gradient HPLC with UV detection and relative response factors. |
| Moisture Content | Karl Fischer Titration | Measures water content volumetrically or coulometrically based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 700-800 C and weighing the residual non-volatile matter. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other regulated metals after acid digestion using plasma emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using an anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures total inorganic residue after treatment with sulfuric acid and ignition; indicates sulfate-forming impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid-to-liquid phase transition occurs, indicating purity and identity. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Measures mass loss upon heating to 105 C under controlled atmosphere, reflecting volatile solvents and moisture. |
| Organic Volatile Impurities (Residual Solvents) | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, toluene, DMF) using capillary GC with flame ionization detection. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water), indicating acidic/basic impurities. |
| Specific Optical Rotation | Polarimetry | Determines optical activity using sodium D-line light to confirm chiral purity and absence of racemization (though 2-hydroxyquinoline is achiral, detects chiral contaminants). |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 126.0 - 130.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.