5-(TRIMETHYLSILYL)-4-PENTYN-1-OL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13224-84-5 |
| Product name | 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Silyl protecting reagent for selective protection of alcohol hydroxyl groups | Deprotonation–substitution reaction with alcohol substrates under inert atmosphere in the presence of a base (e.g., n-BuLi, NaH), yielding silyl ether protected products |
| Pharmaceutical Intermediates | Multifunctional chiral building block containing both alkyne and silyl functionalities, used in synthesis of antitumor and antiviral drug molecules | Serves as a key intermediate in multistep transformations—including Sonogashira coupling, hydrogenation, and oxidation—to introduce alkyne groups and enable subsequent functional group modifications |
| Materials Science | Precursor for organic optoelectronic materials, used to prepare conjugated polymers or small-molecule emissive materials | Terminal alkyne group participates in Glaser coupling or click chemistry (CuAAC) to construct π-conjugated frameworks; trimethylsilyl group modulates solubility and enables subsequent deprotection |
Manufacturing Quality Control of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water in the sample. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing and weighing. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution with phenolphthalein endpoint detection. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of trace metals after acid digestion, based on element-specific atomic emission intensities. |
| Chloride Content | Ion Chromatography (IC) | Separation and quantification of chloride anions using an anion-exchange column and conductivity detection. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Measurement of yellowness intensity by comparing sample absorbance at 430 nm to APHA platinum-cobalt standards. |
| Density at 20 C | Digital Density Meter | Determination of mass per unit volume using oscillating U-tube principle calibrated with air and water. |
| Refractive Index at 20 C | Refractometry | Measurement of light bending angle at air-sample interface using Abbe refractometer or digital equivalent. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Qualitative and quantitative analysis of volatile organic solvents via equilibrium vapor phase sampling and GC-FID. |
| Alkali Metals (Na, K) | ICP-OES | Simultaneous quantification of alkali metal impurities after microwave-assisted acid digestion and plasma excitation. |
| Non-Volatile Residue | Evaporation and Gravimetry | Weighing of residue remaining after evaporation of a fixed sample volume under controlled temperature and vacuum. |
Technical Specifications of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.435–1.445 |
| Relative Density (20°C/25°C) | 0.820–0.840 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
Safety Information of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
Industrial 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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