China Factory Direct
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| CAS number | 132327-80-1 |
| Product name | Nalpha-Fmoc-Ndelta-trityl-L-glutamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used to protect amino acids in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) |
| Chemical Synthesis | Peptide synthesis reagents | Fmoc is applied to protect the α-amino group, while trityl is used to protect side-chain functional groups during synthesis |
| Biotechnology | Synthesis of function-specific peptides | Applied to prepare biologically active peptides with defined sequences and functions |
| Research & Development | Organic synthesis research | Serves as a key building block in organic synthesis for developing and optimizing novel peptide compounds |
| Diagnostics | Peptide synthesis for diagnostic applications | Used to synthesize specific peptide segments for immunoassays or biomarker detection |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color and physical state (typically white to off-white powder), checking for foreign particles or caking. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare infrared absorption spectrum with standard reference spectrum to confirm characteristic functional groups (e.g., aromatic ring and amide bond of Fmoc). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Record ¹H NMR spectrum in deuterated solvent to verify characteristic peaks of molecular structure (e.g., fluorenyl protons of Fmoc, phenyl protons of Trt). | |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase C18 column with UV detection (typically at 210–220 nm or 254 nm) to determine percentage of main peak area for purity assessment (usually required ≥98.0%). |
| Enantiomeric Purity (Optical Purity) | Chiral HPLC or Specific Optical Rotation | Chiral HPLC separates D/L isomers using a chiral stationary phase; specific optical rotation compares measured [α]D value with reference value to confirm L-configuration purity. |
| Moisture Content | Karl Fischer Titration | Determine water content by volumetric or coulometric method (typically required ≤1.0%). |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from synthesis or purification (e.g., DCM, DMF, ethanol) using headspace or direct injection; must comply with ICH Q3C limits. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Measure total content of heavy metals such as lead, arsenic, mercury, and cadmium (typically required ≤20 ppm). |
| Residue on Ignition / Sulfated Ash | Gravimetric Method | Weigh residue after high-temperature ignition to assess inorganic impurity content (typically required ≤0.1%). |
| pH (Solution) | pH Meter | Prepare aqueous solution of defined concentration (e.g., 1%), then measure pH (usually slightly acidic). |
| Fmoc Content | UV-Visible Spectrophotometry (UV-Vis) | Quantify the intact Fmoc protecting group based on its characteristic absorption at ~300 nm. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -14.0±1.5° (c=1, DMF) |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.