3,5-Difluoromandelic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 132741-31-2 |
| Product name | 3,5-Difluoromandelic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,5-Difluoromandelic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,5-Difluoromandelic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,5-Difluoromandelic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antiviral and antitumor agents | Prepared via organic synthesis, including nucleophilic substitution and condensation reactions |
| Agrochemicals | Intermediate for synthesizing novel pesticides | Synthesized via fluorination, esterification, and related processes |
| High-performance materials | Monomer for specialty polymer synthesis | Incorporated into polymer chains via polymerization |
Manufacturing Quality Control of 3,5-Difluoromandelic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., mono-fluoro isomers, des-fluoro analogs, residual solvents) using gradient HPLC-UV with system suitability validation. |
| Residual Solvents (e.g., THF, Ethyl Acetate, Methanol) | GC-FID | Headspace GC with flame ionization detection, calibrated against USP/ICH Q3C-compliant solvent standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, offering sub-pptr detection limits per ICH Q2(R2) and USP <233>. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation; suitable for low-level moisture in hygroscopic organic acids. |
| Optical Rotation | [α]D | Measurement using a digital polarimeter at 20 °C with sodium D-line (589 nm), confirming chiral integrity and enantiomeric excess. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-state transition temperature range per USP <741>, indicating crystallinity and absence of significant eutectic impurities. |
| Chloride Impurity | Ion Chromatography (IC) | Quantitative separation and detection of Cl⁻ anion using suppressed conductivity detection after sample dissolution and filtration. |
| Residual Palladium (from catalytic hydrogenation) | ICP-OES | Post-digestion multi-element analysis by optical emission spectroscopy, compliant with ICH Q3D elemental impurity limits. |
| pH (1% w/v aqueous suspension) | pH Meter | Potentiometric measurement of saturated aqueous suspension to assess acidic character and potential hydrolysis behavior. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by light scattering analysis to verify batch-to-batch consistency in handling and downstream processing. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 600–700 °C followed by weighing of inorganic residue, indicating total inorganic impurities per USP <281>. |
Technical Specifications of 3,5-Difluoromandelic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0 to -19.0 ° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,5-Difluoromandelic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,5-Difluoromandelic acid
Packaging of 3,5-Difluoromandelic acid
Industrial 3,5-Difluoromandelic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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