Ne-Boc-L-lysine tert-butyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13288-57-8 |
| Product name | Ne-Boc-L-lysine tert-butyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ne-Boc-L-lysine tert-butyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ne-Boc-L-lysine tert-butyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ne-Boc-L-lysine tert-butyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthesis of peptide therapeutics | Used as a doubly protected derivative of L-lysine in solid-phase or solution-phase peptide synthesis to prevent side-chain amino group participation in side reactions and improve peptide sequence assembly. |
| Pharmaceutical Chemicals | Preparation of pharmaceutical intermediates | Serves as a key building block for synthesizing active pharmaceutical ingredients (APIs) containing lysine motifs, particularly in reactions requiring further side-chain modification or conjugation. |
| Biochemistry | Development of bioconjugation reagents | Applied in site-specific conjugation of proteins and peptides with drugs, fluorophores, or other biomolecules via selective deprotection. |
| Scientific Research | Structure–activity relationship (SAR) studies | Employed as a building block for synthesizing lysine analogues or derivatives to investigate the relationship between peptide or protein structure and function. |
| Materials Science | Synthesis of functional polymeric materials | Utilized in preparing polylysine-based biomaterials or functional surface-modification materials, where protection group selection controls polymerization degree and material properties. |
Manufacturing Quality Control of Ne-Boc-L-lysine tert-butyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 200–220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., de-Boc, hydrolyzed lysine derivatives) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual tert-butanol, dichloromethane, and ethyl acetate per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Quantification of Pb, Cd, Hg, As, and other toxic elements after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Content | Potentiometric Titration | Titration with standardized silver nitrate solution using a silver indicator electrode to determine chloride ion concentration from HCl salt counterion. |
| Optical Rotation | [α]D | Measurement of specific optical rotation at 589 nm (Na D-line) using a polarimeter to confirm L-configuration and enantiomeric purity. |
| Residual TFA | GC-MS | Headspace GC coupled with mass spectrometric detection to identify and quantify trace trifluoroacetic acid from synthesis. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by laser diffraction analysis to determine D10, D50, D90 values per USP <429>. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of Ne-Boc-L-lysine tert-butyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +11.0 to +13.0 deg (c=1, 6M HCl) |
| Melting Point | 145 to 150 °C (dec.) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ne-Boc-L-lysine tert-butyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ne-Boc-L-lysine tert-butyl ester hydrochloride
Safety Information of Ne-Boc-L-lysine tert-butyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ne-Boc-L-lysine tert-butyl ester hydrochloride
Industrial Ne-Boc-L-lysine tert-butyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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