China Factory Direct
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| CAS number | 133-10-8 |
| Product name | Sodium 4-aminosalicylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Second-line anti-tuberculosis drug | Serves as a raw material for anti-tuberculosis formulations; used alone or in combination with other anti-tuberculosis agents (e.g., streptomycin, isoniazid) to treat pulmonary and extrapulmonary tuberculosis |
| Pharmaceutical Industry | Therapeutic agent for ulcerative colitis | Serves as a raw material for gastrointestinal therapeutics; used in the treatment of ulcerative colitis and segmental enteritis (Crohn’s disease) |
| Pharmaceutical Industry | Pharmaceutical synthesis intermediate | Used in the synthesis of mesalazine (5-aminosalicylic acid) and other salicylic acid derivatives |
| Dye Industry | Dye intermediate | Used in the synthesis of acid dyes, azo dyes, and ice-color dyes (e.g., as diazo components or coupling components) |
| Chemical Reagents | Analytical reagent | Used for colorimetric determination of iron and copper ions, or as an organic synthesis reagent in laboratory applications |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Acid-Base Titration | Quantifies sodium 4-amino salicylate by titration with standardized HCl using bromocresol green indicator. |
| Related Substances | HPLC-UV | Separates and quantifies impurities using reversed-phase C18 column and UV detection at 265 nm. |
| Water Content | Karl Fischer Titration | Measures water content volumetrically via iodine reaction with methanol and sulfur dioxide in pyridine-free reagent. |
| Heavy Metals | AAS (Flame or Graphite Furnace) | Determines total heavy metals (e.g., Pb, Cd, As) after acid digestion by atomic absorption spectroscopy. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after incineration at 600-700 C and weighing. |
| Chloride | Argentometric Titration | Quantifies chloride ions by titration with silver nitrate using potassium chromate indicator. |
| Sulfate | Barium Sulfate Gravimetry | Precipitates sulfate as BaSO4 under acidic conditions and determines mass after ignition. |
| pH of Solution | Potentiometric Measurement | Measures hydrogen ion activity in 1% aqueous solution using calibrated pH electrode. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of a 1% w/v solution against water standard. |
| Particle Size Distribution | Laser Diffraction | Determines particle size distribution by analyzing light scattering pattern of dispersed sample. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens using selective culture media. |
| Loss on Drying | Thermogravimetric Analysis | Measures weight loss after drying at 105 C for 2 hours to determine volatile matter. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
| Melting Point | 145–148 °C |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.