China Factory Direct
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| CAS number | 133-15-3 |
| Product name | Calcium 4-aminosalicylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antitubercular agent for treating tuberculosis resistant to other antitubercular drugs | Administered as a prodrug, metabolized in vivo to para-aminosalicylic acid (PAS) to inhibit folate synthesis in Mycobacterium tuberculosis |
| Pharmaceuticals | Active pharmaceutical ingredient (API) in drug formulations | Formulated into tablets, enteric-coated tablets, or sustained-release dosage forms to improve gastrointestinal tolerability and pharmacokinetic properties |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (C7H6CaN2O4) | Acid-Base Titration with HCl | Direct titration of the calcium salt using standardized hydrochloric acid after dissolution and adjustment to appropriate pH. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using reversed-phase HPLC with UV detection at 265 nm. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element determination of heavy metals by inductively coupled plasma optical emission spectrometry after acid digestion. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue remaining after high-temperature ignition at 700-800 C. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Determination of volatile content by weight loss upon heating to 105 C under controlled conditions. |
| Chloride Impurity | Argentometric Titration (Mohr method) | Titration with silver nitrate using potassium chromate indicator to detect chloride ion concentration. |
| Sulfate Impurity | Barium Sulfate Turbidimetry | Precipitation of sulfate as barium sulfate and quantification via turbidity measurement at 420 nm. |
| Calcium Content | Complexometric Titration with EDTA | Titration with standardized EDTA solution using Eriochrome Black T indicator at pH 10. |
| pH of Aqueous Solution | Potentiometric Measurement | Determination of hydrogen ion activity using calibrated pH electrode in a 1% w/v aqueous suspension. |
| Microbial Limits | Membrane Filtration and Colony Counting | Enumeration of aerobic microorganisms and detection of specified pathogens per pharmacopeial microbiological testing guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 135-140°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.