China Factory Direct
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| CAS number | 133174-15-9 |
| Product name | Fmoc-L-citrulline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Monomer for synthesizing peptide-based drugs | Used as a protected amino acid in solid-phase peptide synthesis |
| Biotechnology | Peptide synthesis for protein structure and function studies | Applied as a protected L-citrulline unit in peptide sequence assembly |
| Pharmaceutical R&D | Peptide construction for drug screening and activity testing | Employed as an Fmoc-protected amino acid derivative in peptide synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, with detection by UV to confirm L-configuration and detect D-isomer impurity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection to quantify common solvents (e.g., DMF, DCM, methanol) per ICH Q3C. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, As) after acid digestion, using plasma optical emission spectroscopy. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration and weighing of residual non-volatile matter. |
| Specific Optical Rotation | Polarimetry | Determination of rotation angle of plane-polarized light in solution to confirm stereochemical integrity and concentration. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-L-ornithine, dipeptide byproducts) using gradient HPLC-UV. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Electrochemical measurement of hydrogen ion activity in aqueous suspension using calibrated pH electrode. |
| Appearance | Visual Inspection | Assessment of physical form, color, and homogeneity against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size via light scattering pattern generated by dispersed particles in air stream. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens following USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 218–222°C |
| Optical Rotation | -11.0 to -8.0° (c=1, in 1M HCl) |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.