4-CHLORO-3-METHYLANISOLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13334-71-9 |
| Product name | 4-CHLORO-3-METHYLANISOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-CHLORO-3-METHYLANISOLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-CHLORO-3-METHYLANISOLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-CHLORO-3-METHYLANISOLE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of pyrethroid insecticides (e.g., lambda-cyhalothrin, beta-cyfluthrin) | Further converted into corresponding acyl chlorides or aldehyde derivatives via diazotization–Sandmeyer reaction or direct chlorination; subsequent condensation and cyclization steps construct the chrysanthemic acid ester backbone |
| Pharmaceuticals | Aromatic ring building block for synthesizing anti-inflammatory agents, antiallergic drugs, and selective 5-HT receptor modulators | Serves as a substituted anisole scaffold in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck); alternatively, demethylation/oxidation introduces phenolic hydroxyl or carboxylic acid groups to construct the pharmacophore core |
| Fine Fragrances | Fixative and modifier in woody and spicy fragrance compositions | Added directly during fragrance compounding (typically ≤0.1% w/w), leveraging its low volatility and mild anise-like odor to enhance olfactive persistence and smoothness |
Manufacturing Quality Control of 4-CHLORO-3-METHYLANISOLE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | Gas Chromatography (GC) with FID or MS detection | Separation and quantification of impurities (e.g., isomers, chlorination by-products) relative to main peak using retention time and response factors. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic solvents (e.g., methanol, dichloromethane) are vaporized in sealed vials and quantified via GC-FID calibration curves. |
| Moisture Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column followed by quantitative detection of chloride based on electrical conductivity. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Atomization and excitation of metals in argon plasma; quantification via element-specific emission line intensity. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., residual 4-chloro-3-methylphenol) using phenolphthalein indicator or potentiometric endpoint detection. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement at 455 nm | Comparison of sample solution color intensity against platinum-cobalt standards or absorbance measurement at specified wavelength. |
| Density at 20 degC | Digital Density Meter (Oscillating U-tube principle) | Measurement of sample density based on resonant frequency shift of a vibrating U-shaped tube filled with the liquid. |
| Refractive Index at 20 degC | Digital Refractometer (Abbe principle) | Determination of refractive index by measuring critical angle of total internal reflection at prism-sample interface. |
| Melting Point | Capillary Melting Point Apparatus | Thermal observation of solid-to-liquid phase transition using controlled heating and optical detection of meniscus movement. |
| Non-Volatile Residue | Gravimetric Analysis after Evaporation | Evaporation of a weighed sample under controlled conditions followed by weighing of residue to determine inorganic/organic non-volatiles. |
Technical Specifications of 4-CHLORO-3-METHYLANISOLE
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.532–1.536 |
| Relative Density (20°C/25°C) | 1.110–1.120 g/cm³ |
| Odor | Characteristic aromatic |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-CHLORO-3-METHYLANISOLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-CHLORO-3-METHYLANISOLE
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Industrial 4-CHLORO-3-METHYLANISOLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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