BOC-D-LEUCINE METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 133467-01-3 |
| Product name | BOC-D-LEUCINE METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-D-LEUCINE METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-D-LEUCINE METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-D-LEUCINE METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for peptide-based drug synthesis | Protected derivative of D-leucine used in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS); BOC group protects the amino functionality, methyl ester activates the carboxyl group |
| Biochemical Research | Construction of model peptide segments containing D-amino acids | Applied to study the effects of D-amino acids on peptide conformation, enzymatic stability, and biological activity |
| Organic Synthesis | Chiral auxiliary or intermediate | Employed in asymmetric synthesis reactions to construct complex molecules with defined stereochemistry |
Manufacturing Quality Control of BOC-D-LEUCINE METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., BOC-D-leucine, D-leucine methyl ester, hydrolysis/degradation products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, dichloromethane, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Optical Rotation | [alpha]D | Measures specific optical rotation at 20 C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700–800 C) and weighing. |
| pH (1% w/v solution) | Potentiometric Titration | Determines acidity/basicity of aqueous solution using calibrated pH electrode. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution by light scattering pattern. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
Technical Specifications of BOC-D-LEUCINE METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +4.0 to +4.5 deg (c=1, in CHCl3) |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-D-LEUCINE METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-D-LEUCINE METHYL ESTER
Packaging of BOC-D-LEUCINE METHYL ESTER
Industrial BOC-D-LEUCINE METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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