China Factory Direct
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| CAS number | 133525-05-0 |
| Product name | PIPERAZINE-2-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of therapeutics for various diseases, including antidepressants and analgesics, via chemical reactions with other compounds to form target drug substances. |
| Medical Research | Biochemical Research | Employed as a biochemical reagent for studying cellular signal transduction and protein function. |
| Chemical Research | Synthetic Chemistry | Applied as an intermediate in organic synthesis to construct complex molecular frameworks. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperazine-2-carboxylic acid dihydrochloride) | Acid-base titration with NaOH | Quantifies active compound by neutralizing HCl salt with standardized sodium hydroxide solution using potentiometric or indicator endpoint detection. |
| Water content | Karl Fischer titration | Determines water by coulometric or volumetric reaction of iodine with water in a methanol-based anhydrous solvent system. |
| Residual solvents | Gas chromatography (GC) with FID | Separates and quantifies volatile organic solvents based on retention time and flame ionization response relative to calibration standards. |
| Heavy metals | ICP-OES | Measures trace metal impurities (e.g., Pb, Cd, Ni) after acid digestion by detecting element-specific atomic emissions in plasma. |
| Chloride content | Potentiometric titration with AgNO3 | Quantifies chloride ions via precipitation with silver nitrate, monitored by silver-ion selective electrode. |
| Related substances | HPLC with UV detection | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV absorbance at 210 nm. |
| Optical purity (enantiomeric excess) | Chiral HPLC | Resolves enantiomers on a chiral stationary phase and calculates enantiomeric excess from peak area ratios. |
| pH of aqueous solution | Potentiometric pH measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Loss on drying | Gravimetric analysis at 105 C | Determines volatile matter by weight loss after drying under specified temperature and vacuum conditions for fixed duration. |
| Particle size distribution | Laser diffraction | Analyzes particle size by measuring angular variation in intensity of laser light scattered by dispersed particles in air or liquid. |
| Microbial contamination | Membrane filtration and colony counting | Detects aerobic microorganisms by filtering sample, culturing on Tryptic Soy Agar, and enumerating viable colonies after incubation. |
| Appearance (color and clarity) | Visual inspection against standard solutions | Evaluates physical state, color (by comparison to APHA/Pt-Co scale), and clarity in solution under controlled lighting conditions. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.