(2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidine-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1335316-40-9 |
| Product name | (2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidine-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1335316-40-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1335316-40-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1335316-40-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for antihypertensive drugs (e.g., sacubitril/valsartan) | Chemical synthesis, chiral resolution, crystallization-based purification |
| Pharmaceuticals | Synthesis precursor for active pharmaceutical ingredients (APIs) used in cardiovascular disease treatments | Enzymatic catalysis, chromatographic separation, quality control |
| Pharmaceutical R&D | Molecular structure modification and optimization of novel drug candidates | Laboratory-scale synthesis, analytical testing |
Manufacturing Quality Control of 1335316-40-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, based on peak area comparison against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation and quantification of enantiomeric impurities using a chiral stationary phase and UV detection, comparing retention times and peak areas. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities by gradient reversed-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of residual organic solvents using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of the residue. |
| pH of Solution | Potentiometric Measurement | Measurement of hydrogen ion activity in aqueous solution using calibrated pH electrode and reference electrode. |
| Specific Optical Rotation | Polarimetry | Determination of chiral compound concentration and enantiomeric integrity via measurement of plane-polarized light rotation in solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed particle size distribution by measuring angular variation in laser light scattering intensity. |
| Microbial Limits | Membrane Filtration | Quantitative detection of aerobic microorganisms using membrane filtration followed by colony enumeration on nutrient agar plates. |
| Endotoxin Content | Kinetic Chromogenic LAL Assay | Quantification of bacterial endotoxins via enzymatic cascade activation of Limulus amebocyte lysate, measured as color development rate. |
Technical Specifications of 1335316-40-9
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C to 146°C |
| Optical Rotation | -28.0° to -32.0° (c=1, in DMF) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1335316-40-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 1335316-40-9
Industrial 1335316-40-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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