4-bromo-2,5-difluorobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 133541-45-4 |
| Product name | 4-bromo-2,5-difluorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-bromo-2,5-difluorobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-bromo-2,5-difluorobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-bromo-2,5-difluorobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing fluorinated insecticides and fungicides | Introduces cyano and halogen groups via nucleophilic substitution or coupling reactions to construct fluorinated heterocyclic structures |
| Pharmaceuticals | Intermediate for synthesizing antitumor and antiviral drugs | Serves as an aryl cyanide precursor in transition metal-catalyzed reactions, including Suzuki coupling and Buchwald-Hartwig amination |
| Materials Science | Monomer for high-performance organic optoelectronic materials | Used to synthesize fluorinated aromatic polymers or small-molecule semiconductors, followed by polymerization or vacuum deposition for thin-film formation |
| Dyes | Intermediate for synthesizing specialty fluorescent dyes and pigments | Introduces chromophores via diazotization, coupling, or cyano hydrolysis to enhance photostability and color fastness |
Manufacturing Quality Control of 4-bromo-2,5-difluorobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., isomers, residual starting materials, by-products) using gradient HPLC-UV against qualified reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., acetonitrile, dichloromethane, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; water reacts stoichiometrically with iodine and sulfur dioxide in methanol medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection after acid digestion; quantifies total heavy metals by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride is quantified using external calibration. |
| Sulfated Ash | Gravimetric Analysis | Sample incineration at 500-600 C followed by sulfuric acid treatment and final ash weighing to determine inorganic residue content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of neat sample under standardized white light against defined references (e.g., USP <901>). |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns from dispersed particles to calculate size distribution by Mie theory. |
| Bulk Density | ASTM D1895 | Measurement of mass per unit volume for freely settled powder in a graduated cylinder under specified tapping conditions. |
| Organic Volatile Impurities (other than solvents) | GC-MS | Identification and semi-quantification of non-solvent volatile organics using gas chromatography coupled with mass spectrometric detection and library matching. |
Technical Specifications of 4-bromo-2,5-difluorobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-bromo-2,5-difluorobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-bromo-2,5-difluorobenzonitrile
Safety Information of 4-bromo-2,5-difluorobenzonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-bromo-2,5-difluorobenzonitrile
Industrial 4-bromo-2,5-difluorobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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