Ethyl 2-Aminoisonicotinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13362-30-6 |
| Product name | Ethyl 2-Aminoisonicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 2-Aminoisonicotinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 2-Aminoisonicotinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 2-Aminoisonicotinate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibacterial drug intermediates | Organic synthesis, condensation reactions |
| Pharmaceuticals | Preparation of key raw materials for antitubercular drugs | Esterification, amidation reactions |
| Agrochemicals | Synthesis of active ingredients for insecticides or fungicides | Modification of heterocyclic compounds |
| Research | Use as ligands or building blocks in materials chemistry research | Molecular self-assembly, coordination chemistry |
Manufacturing Quality Control of Ethyl 2-Aminoisonicotinate
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection, Physical Description | Observe sample color, state (typically white to off-white crystalline powder), odor, and solubility; ensure compliance with physical property requirements specified in pharmacopoeia or enterprise standards. |
| Melting Point | Melting Point Apparatus (Capillary Method) | Determined according to General Chapter 0612 of the Chinese Pharmacopoeia. The melting range of ethyl 2-aminoisonicotinate is typically 120–125°C, used for preliminary assessment of purity and crystal form consistency. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with water-methanol or buffer-acetonitrile as mobile phase. Detection by UV detector at λ=254 nm or 280 nm. Quantify main component using external standard method; typically requires ≥98.0%. |
| Impurity Profile Analysis | High-Performance Liquid Chromatography (HPLC) | Apply gradient or isocratic elution to detect potential impurities such as starting materials (e.g., 2-aminoisonicotinic acid), intermediates, and degradation products (e.g., hydrolysis or oxidation products). Total impurity level generally ≤1.0%. |
| Water Content | Karl Fischer Titration | Quantitative determination of trace moisture using iodine-sulfur dioxide-pyridine-methanol reagent system, in accordance with General Chapter 0832 of the Chinese Pharmacopoeia. Water content is typically controlled at ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Using DB-624 or HP-INNOWAX column with FID detector to analyze residual solvents such as ethanol, ethyl acetate, DMF, etc. Controlled within Permitted Daily Exposure (PDE) limits as per ICH Q3C guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of heavy metals such as lead, cadmium, mercury, and arsenic. Comply with General Chapter 0821 of the Chinese Pharmacopoeia; total heavy metals ≤10 ppm. |
| Chlorides | Turbidimetry or Ion Chromatography | In acidic nitric acid medium, chloride reacts with silver nitrate to form silver chloride precipitate; turbidity measured by turbidimetric method, or directly quantify chloride ion concentration via ion chromatography. Controlled at ≤0.05%. |
| Sulfates | Turbidimetry | Sample treated with hydrochloric acid followed by addition of barium chloride to form barium sulfate precipitate; turbidity measured by turbidimetric method. Controlled at ≤0.02%. |
| pH Value (aqueous solution) | pH Meter Measurement | Prepare a 1% aqueous solution of the sample and measure pH using a calibrated pH meter. Typically controlled within the range of 5.0–7.5 to reflect acid-base stability. |
| UV-Visible Absorption Spectrum | UV-Visible Spectrophotometry (UV-Vis) | Scan between 200–400 nm to determine maximum absorption wavelength (λmax ≈ 250–280 nm) and absorbance; used for identification and auxiliary quantitative verification. |
| Identification Test | Infrared Spectroscopy (IR) or HPLC Retention Time | Compare IR spectrum with reference spectrum for characteristic absorption peaks (e.g., NH₂, C=O, aromatic ring), or confirm structural identity by matching HPLC retention time with reference standard. |
| Microbial Limits | Plate Count Method (Pharmacopoeia General Chapters 1105/1106) | Test for total aerobic microbial count, mold and yeast count, and presence of Escherichia coli. Must meet microbial limits for non-sterile active pharmaceutical ingredients (e.g., total aerobic microbes ≤10³ CFU/g). |
Technical Specifications of Ethyl 2-Aminoisonicotinate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 2-Aminoisonicotinate
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NMR Spectra of Ethyl 2-Aminoisonicotinate
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Industrial Ethyl 2-Aminoisonicotinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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