China Factory Direct
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| CAS number | 13404-22-3 |
| Product name | tert-Butyl L-alaninate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Building block for synthesizing antiviral agents (e.g., adefovir ester derivatives) and peptide-based drugs | Used as a chiral auxiliary in solid-phase peptide synthesis (SPPS); coupled with amino acids after deprotection |
| Organic Synthesis | Chiral building block for preparing β-amino acids, non-natural amino acids, and fluorinated compounds | Undergoes asymmetric Mannich reactions with aldehydes/ketones under basic conditions, or functional group transformations such as diazotization-iodination |
| Pesticide Development | Synthesis of optically active insecticides and plant growth regulators | Introduces a key chiral center into the pesticide molecular scaffold to enhance biological activity and environmental selectivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (L-alanine tert-butyl ester hydrochloride) | Acid-base titration with NaOH | Quantifies active compound by neutralizing HCl salt with standardized NaOH using potentiometric or indicator endpoint detection. |
| Water Content | Karl Fischer titration | Measures water via iodine-sulfur dioxide reaction in methanol-based reagent, with coulometric or volumetric detection. |
| Residual Solvents (e.g., THF, DCM, MeOH) | Gas chromatography (GC-FID) | Separates and quantifies volatile organic solvents using capillary column and flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metal impurities by plasma ionization followed by mass spectrometric quantification. |
| Chloride Impurity | Ion chromatography (IC) | Separates and quantifies chloride anion using suppressed conductivity detection after anion-exchange separation. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Resolves L- and D-enantiomers on a chiral stationary phase and quantifies ee via peak area ratio. |
| Related Substances | Reverse-phase HPLC-UV | Separates and quantifies structurally related impurities using C18 column and UV detection at 200–220 nm. |
| Residual Tert-butanol | Gas chromatography (GC-FID) | Quantifies residual t-butanol by headspace or direct injection GC with FID detection. |
| pH of Aqueous Solution | Potentiometric pH measurement | Determines acidity/basicity of 1% w/v aqueous solution using calibrated pH electrode. |
| Appearance | Visual inspection | Assesses physical state, color, and presence of visible particles or discoloration against standard white background. |
| Melting Point | Capillary melting point apparatus | Determines temperature range at which solid transitions to liquid under controlled heating rate. |
| Loss on Drying | Gravimetric method (105 C, 2 h) | Measures weight loss after drying under specified temperature and time to determine volatile content. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 132-136°C |
| Optical Rotation | +1.0 to +3.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.