China Factory Direct
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| CAS number | 134227-45-5 |
| Product name | 3,4,5-TRIFLUOROBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel fluorinated fungicides and insecticides | Used to construct fluorinated heterocycles or arylamine structures via nucleophilic substitution or coupling reactions with amines, alcohols, or organometallic reagents |
| Pharmaceuticals | Fluorinated aromatic scaffold for anticancer, antiviral, or central nervous system drugs | Employed as a key intermediate in Suzuki coupling, Ullmann coupling, or reductive amination to introduce the trifluorophenyl group into drug molecules |
| Materials Science | Monomer for high-performance fluorinated polymers and liquid crystal materials | Utilized in condensation polymerization with diamines or diols, or as a comonomer in the synthesis of thermally stable aromatic polymers |
| Organic Synthesis | Fluorinated aromatic nitrile reagent for constructing complex molecular frameworks | Applied for cyano group transformations (e.g., hydrolysis to carboxylic acids, reduction to amines) or as an electrophilic partner in metal-catalyzed cross-coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | Gas Chromatography (GC) with FID detector | Separation and quantification of impurities relative to the main peak using retention time and response factor calibration. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic solvents are partitioned into headspace and detected by GC-FID after thermal equilibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of chloride anions on an ion-exchange column followed by quantitative detection via electrical conductivity. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Atomization and excitation of metals in argon plasma; quantification based on element-specific emission intensities. |
| Residue on Ignition | Gravimetric Analysis | Sample is ignited at 700-800 C to volatilize organics; residual inorganic ash is weighed after cooling. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed visually or optically as solid-to-liquid phase change in a calibrated capillary apparatus. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria under controlled lighting conditions. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Bulk Density | Tap Density Measurement | Mass per unit volume determined after mechanically tapping a graduated cylinder containing a known mass of powder. |
| Particle Size Distribution | Laser Diffraction | Analysis of light scattering pattern from dispersed particles to calculate size distribution based on Mie theory. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72–76°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.